Evidence map›Paper›PMID 41578766›Full record

SynthesisThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2026

Co-Occurrence of Inflammatory Bowel Disease in Patients with Vitiligo: A Systematic Review and Meta-Analysis.

Zhaoyi Gu, Jingjing Teng

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhaoyi GuDepartment of Gastroenterology, Suzhou Science & Technology Town Hospital, Suzhou, China.
Jingjing TengDepartment of Gastroenterology, Suzhou Science & Technology Town Hospital, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsInflammatory bowel disease (IBD) is a chronic, increasingly common condition linked to other autoimmune disorders, including vitiligo. This study aims to assess IBD co-occurrence in vitiligo patients to explore underlying immunogenetic factors and inform better screening and management. MATERIALS AND

methodsA systematic search was conducted across Scopus, PubMed/Medline, Web of Science, and Embase, to identify relevant studies published up to March 31, 2025. Studies examining the prevalence of IBD and its subtypes in patients with vitiligo wereincluded. Data were extracted and pooled using random effects models, with heterogeneity assessed through Cochran's Q test andHiggins I2 test.

resultsA total of 16 studies with 44 records were included in the analysis. The pooled prevalence of IBD was 0.97% (95% CI: 0.69-1.25),with Crohn's disease (CD) and ulcerative colitis (UC) reported at 0.45% (0.32-0.59) and 0.69% (0.42-0.97), respectively. Also, vitiligowas significantly associated with an increased risk of IBD (odds ratio [OR] = 1.51, 95% CI: 1.10-2.07), particularly for CD (OR = 1.49, 95%CI: 1.13-1.97). The pooled prevalence of IBD varied across countries, with the highest prevalence reported in Saudi Arabia. Additionally,women with vitiligo had a slightly higher pooled prevalence of IBD compared to men.

conclusionThis study found that the prevalence of IBD in patients with vitiligo is approximately 0.97%, with vitiligo significantly increasing the risk of developing IBD, particularly CD. Clinicians should consider IBD in the differential diagnosis of vitiligo patients withgastrointestinal symptoms.   Cite this article as: Gu Z, Teng J. Co-occurrence of inflammatory bowel disease in patients with vitiligo: a systematic review and meta-analysis. Turk J Gastroenterol. 2026;37(1):3-14.

Indexed as

Crohn DiseaseInflammatory Bowel DiseasesVitiligoAdultColitis, UlcerativeFemaleHumansMalePrevalence

Identifiers

PMID41578766
PMCPMC12824891

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.