Evidence map›Paper›PMID 41578709›Full record

ArticleANZ journal of surgery2026

Skin-Reducing Mastectomy and Implant Reconstruction: Long-Term Surgical, Oncological, and Patient-Reported Outcomes.

Gaik Si Quah, Meagan Brennan, James French, Elisabeth Elder

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Article in ANZ journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Gaik Si QuahWestmead Breast Cancer Institute, Westmead Hospital, Westmead, New South Wales, Australia.ORCID 0000-0002-4355-6717
Meagan BrennanWestmead Breast Cancer Institute, Westmead Hospital, Westmead, New South Wales, Australia.
James FrenchWestmead Breast Cancer Institute, Westmead Hospital, Westmead, New South Wales, Australia.
Elisabeth ElderWestmead Breast Cancer Institute, Westmead Hospital, Westmead, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSkin-reducing mastectomy (SRM) allows implant-based immediate breast reconstruction in women with large, ptotic breasts. This study aimed to evaluate the surgical and patient-reported outcomes (PRO) following SRM.

methodsA retrospective analysis was conducted on patients who underwent SRM between January 2011 and December 2014. Surgical complications, oncological outcomes, and PRO (using BREAST-Q) were collected, with a median follow-up of 10 years.

resultsFifty-five women (95 breasts) underwent SRM and completed the first round of the BREAST-Q questionnaire. 82.3% (n = 45) had SRM for cancer treatment, and the remaining had risk-reducing surgery. 83.6% (n = 46) had direct-to-implant reconstruction, and the remainder had a tissue expander inserted. The mean breast weight was 714 g, and the mean implant volume was 398 mL. The overall complication rate was 58.9%. The most common complication was skin loss due to flap/skin necrosis (24.2%), followed by capsular contracture (18.9%), seroma (7.4%), wound dehiscence (5.3%), implant infection (2.1%), and bleeding (1%). The early implant loss rate was 10.5%. At 10 years (n = 17), the local recurrence rate was 4.4%, the overall survival rate was 97.7%, and the disease-free survival rate was 88.9%. Breast-Q scores were comparable to previous studies (mean score of 65.33). 30.9% of patients (n = 17) completed the modified BREAST-Q questionnaire at 10 years of follow-up. Reconstructed breast satisfaction was high, and 76.5% of patients would choose to undergo SRM again if given the option.

conclusionIn certain patients with larger breasts, SRM can facilitate implant-based immediate breast reconstruction without the need for mesh. Despite relatively high complication rates, patient satisfaction remains high.

Indexed as

Breast ImplantationBreast NeoplasmsMammaplastyMastectomyAdultAgedBreast ImplantsFemaleFollow-Up StudiesHumansMiddle AgedPatient Reported Outcome MeasuresPatient SatisfactionPostoperative ComplicationsRetrospective StudiesTreatment Outcomebreast cancerbreast prosthesis implantationbreast reconstructionmastectomypatient reported outcome

Identifiers

PMID41578709
PMCPMC12953742

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.