Evidence map›Paper›PMID 41578678›Full record

ArticleDevelopmental medicine and child neurology2026

Ophthalmological outcomes, visual perception, fine motor precision, and visual-motor integration in children born very preterm.

Martin Johansson, Eva Larsson, Gerd Holmström, Olga Kochukhova, Lena Hellström-Westas, Ylva F Kaul

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Article in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Martin JohanssonDepartment of Women's and Children's Health, Uppsala University, Sweden.ORCID 0000-0003-0257-5679
Eva LarssonDepartment of Surgical Science, Ophthalmology, Uppsala University, Sweden.
Gerd HolmströmDepartment of Surgical Science, Ophthalmology, Uppsala University, Sweden.
Olga KochukhovaDepartment of Women's and Children's Health, Uppsala University, Sweden.
Lena Hellström-WestasDepartment of Women's and Children's Health, Uppsala University, Sweden.
Ylva F KaulDepartment of Women's and Children's Health, Uppsala University, Sweden.ORCID 0000-0001-8493-3788

Funding

Linnéa och Josef Carlssons StiftelseÖgonfondenStiftelsen Kronprinsessan Margaretas Arbetsnämnd för SynskadadeStiftelsen Promobilia A23127Stiftelsen Promobilia F22092Synskadades Vänner i UppsalaVetenskapsrådet 2016-03109
6 · The paper itself

Abstract

aimTo explore longitudinal associations between ophthalmological outcome and development of visual perception, fine motor precision, and visual-motor integration (VMI) in children born very preterm (gestational age <32 weeks).

methodThis was a prospective longitudinal cohort study of 113 children (51 females, 62 males) born very preterm. Visual acuity, low-contrast visual acuity, stereopsis, and strabismus were investigated at 2 years 6 months (n = 98), 6 years 6 months (n = 84), and 12 years (n = 59). VMI was assessed at 6 years 6 months and 12 years, and visual perception and fine motor precision at 12 years, with the Beery-Buktenica Developmental Test of Visual-Motor Integration. Controls born at term were assessed at 6 years 6 months (n = 64) and 12 years (n = 46).

resultsFor children born preterm, subnormal visual acuity at 2 years 6 months was related to both poorer VMI and fine motor precision at 12 years. Subnormal visual acuity, strabismus, and stereopsis at 6 years 6 months were also related to poorer VMI, visuo-perceptual, and fine motor measures at 12 years. These associations were not present in controls born at term.

interpretationSubnormal ophthalmological function at 2 years 6 months and 6 years 6 months in children born very preterm is related to poorer performance on VMI, visuo-perceptual, and fine motor precision tasks at 12 years, indicating that the quality of visual input interacts with developing visual-motor abilities. The results of this study provide new insights on the relationship between ophthalmological function and neurodevelopment after preterm birth.

Indexed as

Child DevelopmentDepth PerceptionInfant, Extremely PrematureMotor SkillsPsychomotor PerformanceStrabismusVisual AcuityVisual PerceptionChildChild, PreschoolFemaleHumansInfant, NewbornLongitudinal StudiesMaleProspective Studies

Identifiers

PMID41578678
PMCPMC13436713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.