Trio-colored appraisal of an eco-conscious method for the determination of bisphenol A in drinking water bottles and pharmaceutical eye-drop solutions.

Farah S Elbitar, Lobna A Hussein, Noha M El Zahar, Hend Z Yamani, Fotouh R Mansour

Abstract read

In one paragraph

Article in BMC chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Farah S ElbitarMedicinal Chemistry Department, Faculty of Pharmacy, King Salman International University (KSIU), Ras Sudr, South Sinai, 46612, Egypt.ORCID http://orcid.org/0009-0007-1227-688X

Lobna A HusseinPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Organization of African Unity Street, Abbassia, 11566, Cairo, Egypt.

Noha M El ZaharPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Organization of African Unity Street, Abbassia, 11566, Cairo, Egypt.ORCID http://orcid.org/0000-0002-2397-3361

Hend Z YamaniPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Organization of African Unity Street, Abbassia, 11566, Cairo, Egypt.ORCID http://orcid.org/0000-0002-9423-5008

Fotouh R MansourMedicinal Chemistry Department, Faculty of Pharmacy, King Salman International University (KSIU), Ras Sudr, South Sinai, 46612, Egypt. fotouh.rashed@ksiu.edu.eg.ORCID http://orcid.org/0000-0003-0847-4035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) is a hazardous endocrine-disrupting compound which is frequently detected in water sources due to its extensive application in plastic manufacturing. This study introduces an environmentally sustainable liquid-liquid microextraction (LLME) approach, coupled with high-performance liquid chromatography with diode-array detection (HPLC/DAD), for the determination of BPA in drinking water bottles and pharmaceutical eye-drop solutions. 1-Decanol was employed as a green extraction solvent, and critical experimental parameters were systematically optimized to achieve maximum extraction efficiency. Furthermore, the mobile phase consisted of ethanol and water (40:60 v/v), both recognized as green solvents, further enhancing the method's eco-friendly profile. The developed method demonstrated accepted linearity (r = 0.9989) within the concentration range of 25-20,000 ng mL

Indexed as

Bisphenol AEndocrine disruptorsGreen analytical chemistryLiquid-liquid microextractionWater analysis

Identifiers

PMID41578321

DOI10.1186/s13065-025-01713-w

PMCPMC12911365

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.