Evidence map›Paper›PMID 41578280›Full record

SynthesisBMC oral health2026

Prevalence of early childhood caries in Southern Africa: systematic review and meta-analysis.

Oluwasayo Bolarinwa Ogunlade, Richard Akinjide Adu, Adebukunola Olajumoke Afolabi, Folahanmi Tomiwa Akinsolu, Adebola Oluyemisi Ehizele, George Uchenna Eleje, Oliver Chukwujekwu Ezechi, Qudus Olajide Lawal, Ahmed Bhayat, Moréniké Oluwátóyìn Foláyan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Oluwasayo Bolarinwa OgunladeDepartment of Nursing Science, Obafemi Awolowo University, Ile-Ife, Nigeria. sayoogunlade@oauife.edu.ng.
Richard Akinjide AduDepartment of Psychology, Osun State University, Osogbo, Nigeria.
Adebukunola Olajumoke AfolabiDepartment of Nursing Science, Faculty of Basic Medical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
Folahanmi Tomiwa AkinsoluDepartment of Public Health, Faculty of Basic Medical and Health Sciences, Lead City University, Ibadan, 110115, Nigeria.
Adebola Oluyemisi EhizeleDepartment of Periodontics, School of Dentistry, College of Medical Sciences, University of Benin, Benin, Nigeria.
George Uchenna ElejeDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.
Oliver Chukwujekwu EzechiDepartment of Public Health, Faculty of Basic Medical and Health Sciences, Lead City University, Ibadan, 110115, Nigeria.
Qudus Olajide LawalDepartment of Obstetrics and Gynaecology, Irrua Specialist Teaching Hospital, Irrua, Nigeria.
Ahmed BhayatDepartment of Community Dentistry, University of Pretoria, Pretoria, South Africa.
Moréniké Oluwátóyìn FoláyanDepartment of Child Dental Health, Obafemi Awolowo University, Ile-Ife, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is currently no comprehensive pooled analysis or regional synthesis previously been conducted on the prevalence of early childhood caries (ECC) in the Southern Africa region. This study determined the prevalence of ECC and its associated risk factors in the Southern African region.

methodsThe systematic review and meta-analysis were registered with PROSPERO (CRD420251004718). PubMed, Scopus, Web of Science, and AJOL databases were searched up to April 2025. Studies were included if they were cross-sectional, cohort, or case-control. had to be published between 1st January 2000 and 31st March 2025 and had to report the prevalence of ECC and associated risk factors in Southern Africa. There were no language restrictions. Studies among children with special needs were excluded. Heterogeneity was evaluated using the I² statistic, while a random-effects model was applied to estimate the overall prevalence of dental caries. The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. It utilised the Joanna Briggs Institute Critical Appraisal Checklist to assess the methodological quality of the studies.

resultsA total of 113 publications were identified through databases, and 15 publications (including 25,935 children) met the eligibility criteria for the systematic review and nine for the meta-analysis. The pooled prevalence of ECC in Southern Africa was 52% (95% CI: 44 to 59%; p < 0.00001). Studies with sample sizes greater than 500 reported an ECC prevalence of 53% (95% CI: 41–65%), while those with fewer than 500 participants reported a prevalence of 50% (95% CI: 46–54%). Hospital-based and school-based studies each reported a prevalence of ECC of 49% while studies conducted in mixed settings reported a higher prevalence of 72%. The prevalence of ECC was higher among males at 51% (95% CI: 42–61%) compared to females at 46% (95% CI: 38–54%). The risk factors associated with ECC include sociodemographic and environmental risk factors, oral hygiene practices, feeding practices, dietary habits and sugar consumption, and access to dental care and fluoride exposure.

conclusionsThe prevalence of ECC in Southern Africa is high, driven by behavioural, environmental, and sociodemographic factors. The results highlight the critical need for tailored preventive measures, such as better oral hygiene, appropriate feeding and dietary habits, and increased access to fluoride-based care to support effective policy and planning to reduce the prevalence of ECC.

Indexed as

Dental CariesAfrica, SouthernChild, PreschoolHumansPrevalenceRisk FactorsCariesDmftPrimary dentitionPufaSouthern africa countries

Identifiers

PMID41578280
PMCPMC12910840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.