Evidence map›Paper›PMID 41578252›Full record

SynthesisBMC musculoskeletal disorders2026

Prevalence of hip and knee osteoarthritis in Europe: a systematic review and meta-analysis.

Ioannis Christofides, Ioannis Vavliakis, Huub H de Klerk, Melle Broekman, Cees C Verheyen, Job N Doornberg

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ioannis ChristofidesDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. i.christofides@umcg.nl.
Ioannis VavliakisDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Huub H de KlerkDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Melle BroekmanDepartment of Surgery and Perioperative Care, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Cees C VerheyenDepartment of Orthopaedic Surgery and Traumatology, Isala Hospital, Zwolle, The Netherlands.
Job N DoornbergDepartment of Orthopaedic Surgery and Traumatology, University Medical Centre Groningen, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOsteoarthritis (OA) is a leading cause of pain and disability worldwide, with the hip and knee being the most commonly affected major joints. These forms of OA contribute substantially to individual suffering, reduced quality of life, and increased healthcare costs. While global estimates of OA prevalence are available, there is a paucity of reliable, region-specific data for Europe. This systematic review aims to address the following questions: (1) What is the prevalence of hip and knee OA in Europe? (2) How does this prevalence vary across different regions? (3) How does the reported prevalence differ depending on the diagnostic methods used?

methodsA systematic literature search was conducted in PubMed and Embase for studies published between January 1, 2000, and November 14, 2024. Study quality and risk of bias were assessed independently using the Joanna Briggs Institute (JBI) checklist. Pooled prevalence estimates were calculated using random-effects meta-analysis, and subgroup analyses were performed by diagnostic method and geographic region. The review was prospectively registered with PROSPERO (CRD42022302976) and conducted in accordance with PRISMA guidelines.

resultsTwenty nine studies were included, comprising data from 6,767,340 individuals for hip OA and 6,805,777 for knee OA. The pooled prevalence of hip OA in Europe was estimated at 6% (95% CI: 3-9%), and for knee OA, 10% (95% CI: 7-14%). Subgroup analysis by diagnostic method revealed that prevalence was highest for hip OA when using Kellgren-Lawrence grade ≥ 2 (11.5%, 95% CI: 5.0-24.5%) and for knee OA when using American College of Rheumatology (ACR) criteria (14.5%, 95% CI: 7.6-25.9%). Subgroup analysis by European region showed that hip OA prevalence ranged from 2% in Eastern Europe to 7% in Southern Europe, while knee OA ranged from 7% in Northern Europe to 19% in Eastern Europe.

conclusionHip and knee OA are common in Europe, though prevalence varies widely across studies and diagnostic approaches.

Indexed as

Osteoarthritis, HipOsteoarthritis, KneeEuropeHumansPrevalenceEuropeHipKneeOsteoarthritisPrevalence

Identifiers

PMID41578252
PMCPMC12911254

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.