Evidence map›Paper›PMID 41577952›Full record

ArticleScientific reports2026

A transpupillary approach for crosslinking Guinea pig sclera using WST11 and near-infrared light.

Demi H J Vogels, Yusupjan Abdulla, William Myles, Sara Cummings, Lilach Agemy, Tamar Yechezkel, Arie L Marcovich, Avigdor Scherz, Vanessa L S LaPointe, Sally A McFadden and 1 more

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Demi H J VogelsDepartment of Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht, The Netherlands.
Yusupjan AbdullaSchool of Psychology, The University of Newcastle, Callaghan, NSW, Australia.
William MylesSchool of Psychology, The University of Newcastle, Callaghan, NSW, Australia.
Sara CummingsSchool of Psychology, The University of Newcastle, Callaghan, NSW, Australia.
Lilach AgemyDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot, Israel.
Tamar YechezkelDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot, Israel.
Arie L MarcovichDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot, Israel.
Avigdor ScherzDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot, Israel.
Vanessa L S LaPointeDepartment of Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht, The Netherlands. v.lapointe@maastrichtuniversity.nl.
Sally A McFadden *School of Psychology, The University of Newcastle, Callaghan, NSW, Australia.
Mor M Dickman *Department of Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crosslinking strengthens the sclera and holds potential as a treatment for myopia. This study aims to identify optimal crosslinking parameters in guinea pigs using WST11 with dextran followed by near-infrared (NIR) illumination. Guinea pig eyes were incubated in WST11 with 2, 5 or 10% dextran, and penetration depth was assessed by fluorescence microscopy. Crosslinking efficacy was measured as thermal stability using a thermal degradation assay, following incubation in WST11 + 10% dextran (WST-D) for 30 min and NIR irradiation at 10 mW/cm

Indexed as

Cross-Linking ReagentsDextransInfrared RaysMyopiaScleraAnimalsGuinea PigsCross-Linking ReagentsDextrans

Identifiers

PMID41577952
PMCPMC12902051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.