Evidence map›Paper›PMID 41577943›Full record

ArticleEcoHealth2026

Diverse Reservoirs of Third-Generation Cephalosporin-Resistant Escherichia coli in Guatemala.

Gabriela Perez-Garcia, Danilo Alvarez, Andrea Gomez Barillas, Renata Mendizabal-Cabrera, Brooke M Ramay, Tin Ho, Nikolina Walas, Jay P Graham

Abstract read
In one paragraph

Article in EcoHealth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabriela Perez-GarciaDepartment of Epidemiology and Biostatistics, School of Public Health, University of California, 2121 Berkeley Way, Berkeley, CA, 94704, USA. gperez-garcia@berkeley.edu.ORCID 0009-0001-6305-1476
Danilo AlvarezCentro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Andrea Gomez BarillasCentro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City, Guatemala.ORCID 0000-0002-1677-732X
Renata Mendizabal-CabreraCentro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City, Guatemala.ORCID 0000-0002-5616-6654
Brooke M RamayCentro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City, Guatemala.ORCID 0000-0001-8527-4067
Tin HoEnvironmental Health Sciences Division, School of Public Health, University of California, Berkeley, CA, USA.ORCID 0000-0001-9635-1769
Nikolina WalasEnvironmental Health Sciences Division, School of Public Health, University of California, Berkeley, CA, USA.
Jay P GrahamEnvironmental Health Sciences Division, School of Public Health, University of California, Berkeley, CA, USA.ORCID 0000-0001-7062-6293

Funding

Zoonotic Uropathogenic Escherichia coli in Northwest Ecuador: Incidence and Risk FactorsR01AI167989 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joseph N. S. Eisenberg, Jay Paul Graham · 2022 to 2026
$3.6M
Antimicrobial Resistance Transmission Associated with Small-Scale Food-Animal Production in Peri-Urban Communities of Quito, EcuadorR01AI135118 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI GRAHAM, JAY PAUL · 2018 to 2021
$2.0M
NHLBI NIH HHS R01AI135118NHLBI NIH HHS R01AI167989
6 · The paper itself

Abstract

In Guatemala, there is a significant gap in our understanding of the prevalence of antibiotic resistance across different reservoirs likely to affect human exposures. We conducted a One Health study of produce, poultry, water, and humans within peri-urban and urban Guatemalan markets to characterize the prevalence of third-generation cephalosporin-resistant Escherichia coli (3GCR-EC). We screened a total of 132 samples for 3GCR-EC using selective media. Samples were collected across three markets in Guatemala and included produce (n = 32), public tap water (n = 30), commercial and non-commercial poultry (n = 40), and human fecal matter (n = 30). We measured phenotypic and genotypic resistance using culture-based methods and whole-genome sequencing. Among the 132 samples, 87.1% (n = 115) were positive for E. coli, and 67.4% (n = 43) were positive for 3GCR-EC. After removing duplicates, a total of 40 3GCR-EC isolates were sequenced from commercial chicken carcasses (n = 8), non-commercial chicken carcasses (n = 16), water (n = 4), and human feces (n = 12). Out of 11 unique extended-spectrum beta-lactamase genes, the most prevalent gene was bla

Indexed as

Anti-Bacterial AgentsEscherichia coliAnimalsCephalosporinsEscherichia coli InfectionsFecesGuatemalaHumansPoultryThird Generation CephalosporinsAnti-Bacterial AgentsCephalosporinsThird Generation Cephalosporinsantibiotic resistanceEscherichia coliextended-spectrum β-lactamasesGuatemalaone Healththird-generation cephalosporin resistance

Identifiers

PMID41577943
PMCPMC13287249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.