Evidence map›Paper›PMID 41577940›Full record

ArticleScientific reports2026

A functional and robust cellular model for high-throughput screening of piezo1 modulators.

Xueying Liu, Kai Zheng, Yanyan Wang, Liu Yang, Shuang Chen, Cheng Hu, Haojian Han, Wansheng Zhang, Kai Qin, Feng Hao and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xueying Liu *College of Laboratory Medicine, Jilin Medical University, Jilin, 132013, China.
Kai Zheng *College of Laboratory Medicine, Jilin Medical University, Jilin, 132013, China.
Yanyan WangCollege of Laboratory Medicine, Jilin Medical University, Jilin, 132013, China.
Liu YangCollege of Laboratory Medicine, Jilin Medical University, Jilin, 132013, China.
Shuang ChenCollege of Pharmacy, Jilin Medical University, Jilin, 132013, China.
Cheng HuCollege of Laboratory Medicine, Jilin Medical University, Jilin, 132013, China.
Haojian HanCollege of Laboratory Medicine, Jilin Medical University, Jilin, 132013, China.
Wansheng ZhangUrology Department, Affiliated Hospital of Jilin Medical University, Jilin, 132013, China.
Kai Qin *Jilin Changyuan Pharmaceutical Co, Changchun, 130103, China. qinkai@jemincare.com.
Feng Hao *College of Laboratory Medicine, Jilin Medical University, Jilin, 132013, China. haof863@nenu.edu.cn.
Wei Zhou *Jilin Changyuan Pharmaceutical Co, Changchun, 130103, China. zhouwei5@jemincare.com.

Funding

Education Department of Jilin Province JJKH20240596KJGraduate Innovation Program of Jilin Medical University 2023zyc04Jilin Medical University 2024 College Students' Innovation and Entrepreneurship Training Program S202413706007"Meikang Shengde" Student Research and Innovation Fund 2023JYMKZ002National Natural Science Foundation of China 81173109Scientific and Technological Planning Project of Jilin Province YDZJ202401007ZYT5
6 · The paper itself

Abstract

The Piezo1 channel, a mechanosensitive non-selective cation channel, plays a critical role in mediating calcium (Ca

Indexed as

High-Throughput Screening AssaysIon ChannelsAnimalsCalciumHEK293 CellsHumansModels, BiologicalCalciumIon ChannelsPIEZO1 protein, humanANO1Cellular modelDrug screeningHTSPiezo1

Identifiers

PMID41577940
PMCPMC12902066

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.