Evidence map›Paper›PMID 41577915›Full record

ArticleAdvances in experimental medicine and biology2026

Photobiomodulation Increases Eye Movement Conjugation in Healthy Volunteers.

Alex O Trofimov, Elizabeth Kalinkina, Alexander Lazarev, Anastasia Kivenko, Edwin M Nemoto, Olga A Bragina, Denis E Bragin

Abstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alex O TrofimovDepartment of Neurological Diseases, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.
Elizabeth KalinkinaDepartment of Neurological Diseases, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.
Alexander LazarevDepartment of Neurological Diseases, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.
Anastasia KivenkoDepartment of Neurological Diseases, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.
Edwin M NemotoDepartment of Neurology, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Olga A BraginaLovelace Biomedical Research Institute, Albuquerque, NM, USA.
Denis E BraginDepartment of Neurology, University of New Mexico School of Medicine, Albuquerque, NM, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to evaluate changes in eye movement conjugation in healthy volunteers in response to transcranial photobiomodulation (tPBM). MATERIALS AND

methods54 healthy volunteers (23 men, 31 women; median age was 23.5 years) were included in this retrospective, non-randomized study. Eye tracking (ET) was performed using the iPad app EyeTracker with a sampling rate of 20 Hz before and after 10 min tPBM (810 nm). The tracker calculated angular velocities in the vertical and horizontal planes (AV; vertical and horizontal). Data are shown as a median [interquartile range]. Pearson's correlation coefficients were used to assess agreement between computed variables. This coefficient value was designated as the vergence reactivity index (VRx), which reflects the eye movement conjugation. The differences were determined using the Wilcoxon T-criterion. The level of significance was p < 0.05.

resultsVertical and horizontal VRx after tPBM were significantly higher than before the procedure: 0.878 [0.843; 0.902] vs. 0.783 [0.702; 0.829], p < 0.001, respectively and 0.875 [0.834; 0.912] vs. 0.927 [0.921; 0.93], p < 0.001, respectively.

conclusionTranscranial PBM causes a significant increase in vertical and horizontal vergence indices, which indicates an improvement in eye movement conjugation in healthy volunteers.

Indexed as

Eye MovementsLow-Level Light TherapyAdultEye-Tracking TechnologyFemaleHealthy VolunteersHumansMaleRetrospective StudiesYoung AdultEye movements conjugationEye trackingPhotobiomodulation

Identifiers

PMID41577915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.