Evidence map›Paper›PMID 41577914›Full record

ArticleAdvances in experimental medicine and biology2026

Physiological Effects of Photobiomodulation Therapy in the Treatment of Multiple Concussions.

Fazle Kibria, Olga A Bragina, Eduardo Colombari, Alexey Trofimov, Oxana Semyachkina-Glushkovskaya, Edwin M Nemoto, Dmitriy N Atochin, Satoshi Kashiwagi, Patric Stanton, Denis E Bragin

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Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fazle KibriaLovelace Biomedical Research Institute, Albuquerque, NM, USA.
Olga A BraginaLovelace Biomedical Research Institute, Albuquerque, NM, USA.
Eduardo ColombariSão Paulo State University, Araraquara, Brazil.
Alexey TrofimovPrivolzhsky Research Medical University, Nizhny Novgorod, Russia.
Oxana Semyachkina-GlushkovskayaSaratov State University, Saratov, Russia.
Edwin M NemotoUniversity of New Mexico School of Medicine, Albuquerque, NM, USA.
Dmitriy N AtochinBoston VA Medical Center West Roxbury, Veterans Affairs Boston Healthcare System and Harvard Medical School, West Roxbury, MA, USA.
Satoshi KashiwagiMassachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Patric StantonNew York Medical College, Valhalla, NY, USA.
Denis E BraginLovelace Biomedical Research Institute, Albuquerque, NM, USA. dbragin@lovelacebiomedical.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repeated concussion traumatic brain injury (TBI) results in long-term brain damage and cognitive dysfunctions, leading to neurodegenerative diseases. The brain clearance system plays a crucial role in TBI recovery and neurodegenerative disease amelioration by draining waste macromolecules from the brain. Pharmacological therapeutics have failed to demonstrate benefits in human TBI. Photobiomodulation (PBM) has gained interest in neuroscience and has been shown to improve brain drainage. Here, we evaluated the efficiency of PBM in the treatment of multiple concussions in mice and the augmentation of the brain clearance system. Three consecutive closed-head concussive TBIs were induced with a 1-h interval to the left hemisphere in C57BL/6 male mice. A near-infrared irradiation (1270 nm, 10 mW/cm

Indexed as

BrainBrain ConcussionLow-Level Light TherapyAnimalsCerebrovascular CirculationDisease Models, AnimalMaleMiceMice, Inbred C57BLMicrocirculationBrain complianceCerebral blood flowConcussionMeningeal lymphaticsOxygen delivery to tissuePhotobiomodulationTraumatic brain injury

Identifiers

PMID41577914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.