Evidence map›Paper›PMID 41577911›Full record

ArticleAdvances in experimental medicine and biology2026

Capillary Red Blood Cell Velocity Is Decreased in Skeletal Muscle of Septic Rats: In Vivo Imaging Using Videocapillaroscopy.

Rin Kataoka, Naoki Hitosugi, Kazuki Hotta, Narumi Fukuzaki, Kota Izawa, Shuri Arai, Tomotaka Koike, Kentaro Kamiya, Atsuhiko Matsunaga

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Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Rin KataokaGraduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Naoki HitosugiDepartment of Rehabilitation, St. Marianna University Yokohama Seibu Hospital, Yokohama, Japan.
Kazuki HottaGraduate School of Medical Sciences, Kitasato University, Sagamihara, Japan. hotta.kazuki@kitasato-u.ac.jp.
Narumi FukuzakiGraduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Kota IzawaGraduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Shuri AraiGraduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Tomotaka KoikeDepartment of Intensive Care Center, Kitasato University Hospital, Sagamihara, Japan.
Kentaro KamiyaGraduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Atsuhiko MatsunagaGraduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the impact of sepsis on red blood cell (RBC) velocity, diameter, and categories of skeletal muscle capillaries 3-4 h after sepsis onset. Male Wistar rats (9-11 weeks old, n = 14) were randomly classified into sham and cecal ligation and perforation (CLP) groups, respectively. In vivo imaging of capillaries in the spinotrapezius muscle was performed using stain-free videocapillaroscopy. RBC velocity and capillary diameter were analyzed. Capillaries were classified into three groups: (1) continuously flowing capillaries defined as maintaining continuous flow for >30 s; (2) intermittently flowing, showing brief stagnation lasting <10 s; (3) stopped-flow, showing no flow for >10 s during 30 s of observation periods. The number of capillaries in each category is compared between the groups. The RBC velocity of the CLP group was significantly lower than that of the sham group (p = 0.01), but the capillary diameter was not different between the groups. The CLP group showed a trend of a weak negative correlation between capillary diameter and RBC velocity (r

Indexed as

CapillariesErythrocytesMicroscopic AngioscopyMuscle, SkeletalSepsisAnimalsBlood Flow VelocityDisease Models, AnimalMaleMicrocirculationRatsRats, WistarCapillary imagingMicrocirculationRed blood cell velocitySepsisSkeletal muscle

Identifiers

PMID41577911

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.