Evidence map›Paper›PMID 41577902›Full record

ArticleAdvances in experimental medicine and biology2026

A Portable Broadband Near-Infrared Spectroscopy Device for In Vivo Oxygenation and Metabolism Measurements.

Musa Talati, Frédéric Lange, Dimitrios Airantzis, Danial Chitnis, Temisan Ilukwe, Darshana Gopal, Paola Pinti, Niccole Ranaei-Zamani, Olayinka Kowobari, Sarah Johnson and 6 more

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Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Musa TalatiDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK. musa.talati.20@ucl.ac.uk.
Frédéric LangeDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Dimitrios AirantzisDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Danial ChitnisDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Temisan IlukweDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Darshana GopalDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Paola PintiDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Niccole Ranaei-ZamaniEGA Institute for Women's Health, University College London, London, UK.
Olayinka KowobariEGA Institute for Women's Health, University College London, London, UK.
Sarah JohnsonEGA Institute for Women's Health, University College London, London, UK.
Olivia NewthEGA Institute for Women's Health, University College London, London, UK.
Sara HillmanEGA Institute for Women's Health, University College London, London, UK.
Dimitrios SiassakosEGA Institute for Women's Health, University College London, London, UK.
Anna L DavidEGA Institute for Women's Health, University College London, London, UK.
Subhabrata MitraEGA Institute for Women's Health, University College London, London, UK.
Ilias TachtsidisDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Broadband NIRS (bNIRS) is an extension of fNIRS that provides the same assessment of oxygenation biomarkers along with a valuable marker for oxygen metabolism at a cellular level, the oxidation state of cytochrome-c-oxidase (oxCCO). bNIRS implements many (100s) wavelengths in the NIR spectrum to address this and provide insight into tissue energetics. To supply these many wavelengths of light, broadband sources are required, and spectrometers are employed to distinguish power per wavelength. Current multi-channel bNIRS instruments are bulky and only semi-portable due to technological limitations. We propose a design for a bNIRS device that has been miniaturised to allow for portable use. This design leverages the innovations in photonic devices that have created a new line of SMD-type micro-spectrometers and broadband NIR high-power LEDs. This first-of-its-kind device, referred to as microCYRIL (after its two predecessors CYRIL and miniCYRIL), has been developed for oxygenation and metabolism measurements with dual channel operation. To validate functionality, concentration changes in oxygenated (HbO

Indexed as

OxygenAnimalsElectron Transport Complex IVEquipment DesignHumansMiniaturizationOxyhemoglobinsSpectroscopy, Near-InfraredElectron Transport Complex IVOxygenOxyhemoglobinsbNIRSCytochrome-C-oxidaseFunctionalHaemoglobinInstrumentation

Identifiers

PMID41577902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.