Evidence map›Paper›PMID 41577900›Full record

ArticleAdvances in experimental medicine and biology2026

Letting Biology Validate the EPR Imaging of Tumor pO

Inna Gertsenshteyn, Lucas Berens, Boris Epel, Eugene Barth, Richard C Miller, Subramanian V Sundramoorthy, Mihai Giurcanu, John Lukens, Kayla Hall, Viktor M Tormyshev and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Inna GertsenshteynDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Lucas BerensDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Boris EpelDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Eugene BarthDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Richard C MillerDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Subramanian V SundramoorthyDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Mihai GiurcanuDepartment of Public Health, University of Chicago, Chicago, IL, USA.
John LukensDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Kayla HallDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Viktor M TormyshevNovosibirsk Institute of Organic Chemistry, Novosibirsk, Russia.
Bulent AydoganDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Ralph R WeichselbaumDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Mrignayani KotechaO2M Technologies, Chicago, IL, USA.
Chin-Tu ChenCenter for EPR Imaging In Vivo Physiology, University of Chicago, Chicago, IL, USA.
Howard J HalpernDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA. hhalpern@uchicago.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxic resistance of living tissue to cytotoxin, most notably radiation, has been known for over a century but was believed in early trials to be a universal characteristic of all tumors. Oxygen electrode measurements of tumor pO

Indexed as

OxygenTumor HypoxiaAnimalsCell Line, TumorElectron Spin Resonance SpectroscopyHumansMiceOxygenEPRpO2 ImagingRadiation BoostsTumor Control

Identifiers

PMID41577900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.