Evidence map›Paper›PMID 41577898›Full record

ArticleAdvances in experimental medicine and biology2026

A Novel Approach to In Vivo EPR Spectroscopy for Repeatable Assessments of Oxygenation Levels in Tumors at Any Depth: Preliminary Feasibility Studies Utilizing a Multisite Oxygen Sensor Inside HDR Brachytherapy Needles.

Daniela Olivera Velarde, Erik Pearson, Yasmin Hasan, Boris Epel, Subramanian Sundramoorthy, Wilson Schreiber, Bulent Aydogan, Ann Barry Flood, Howard Halpern, Harold M Swartz

Abstract read
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In one paragraph

Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniela Olivera VelardeDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Erik PearsonDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Yasmin HasanDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Boris EpelDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Subramanian SundramoorthyDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Wilson SchreiberClin-EPR, LLC, Lyme, NH, USA.
Bulent Aydogan *Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Ann Barry Flood *Clin-EPR, LLC, Lyme, NH, USA.
Howard Halpern *Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Harold M Swartz *Clin-EPR, LLC, Lyme, NH, USA. harold.swartz@dartmouth.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is widespread consensus that hypoxia limits the effectiveness of cancer therapy. This has led to interventions to increase oxygen (O

Indexed as

BrachytherapyNeoplasmsOxygenAnimalsElectron Spin Resonance SpectroscopyFeasibility StudiesHumansMiceNeedlesTumor HypoxiaOxygenElectron paramagnetic resonanceHypoxia in tumorsIn vivo oxygen measurements

Identifiers

PMID41577898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.