Evidence map›Paper›PMID 41576313›Full record

ArticleNeurology2026

Stroke Technology Diffusion in Rural Settings: Differential Exposure to Certification Levels by Community Income Levels.

Yu-Chu Shen, Maya Spencer, Renee Y Hsia

Abstract read
In one paragraph

Article in Neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu-Chu ShenDepartment of Defense Management, Naval Postgraduate School, Monterey, CA.ORCID 0000-0003-1097-0345
Maya SpencerDepartment of Emergency Medicine, University of California, San Francisco; and.
Renee Y HsiaDepartment of Emergency Medicine, University of California, San Francisco; and.ORCID 0000-0001-9819-6926

Funding

NBER Center for Aging and Health Research-Post COVID-19 Experiences Among Adults with ADRDP30AG012810 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI DAVID M CUTLER, Karen Ellen Joynt Maddox · 1999 to 2026
$24.6M
Structural Racism and Discrimination in the Expansion of Hospital Stroke Care Capacity: A Multi-Level Analysis on Access to Care, Treatment, and OutcomesR01MD017482 · NIMHD · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI HSIA, RENEE YUEN-JAN, SHEN, YU-CHU · 2022 to 2025
$2.2M
NIA NIH HHS P30 AG012810NIMHD NIH HHS R01 MD017482
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAlthough stroke technology and care infrastructure have advanced significantly, it remains unclear whether recent expansions of certified stroke centers have benefited rural patients equitably across income levels. This study assessed whether rural communities of varying income experienced similar gains in access to certified stroke centers and whether such expansions were associated with improvements in acute stroke treatment and outcomes.

methodsWe conducted a retrospective cohort study using 100% Medicare Provider and Analysis Review data from January 1, 2009, to December 31, 2019. This study included all Medicare fee-for-service beneficiaries diagnosed with acute ischemic stroke who resided in rural US communities. Communities were classified as exposed if a newly certified stroke center-acute stroke ready hospital (ASRH), primary stroke center, thrombectomy-capable stroke center (TSC), or comprehensive stroke center (CSC)-opened within a 30-minute drive. A community fixed-effects linear probability model was used to evaluate changes in outcomes after stroke center certification. Primary outcomes included the following: (1) admission to a stroke-certified hospital, (2) receipt of thrombolytic therapy, (3) receipt of thrombectomy, and (4) one-year mortality.

resultsAmong 590,191 rural stroke patients, 4% of low-income and 22% of high-income patients had access to a nearby certified stroke center in 2009. By 2019, 30% of low-income and 50% of high-income communities had gained access to at least 1 newly certified stroke center; high-income communities were 3 times more likely than low-income communities to be exposed to a newly certified TSC or CSC (5.4% vs 1.8%). Exposure to ASRHs increased the probability of thrombolysis by 0.63 percentage points (95% 0.05-1.22), whereas exposure to TSC/CSCs increased the probability by 1.39 points (95% CI 0.28-2.49) and thrombectomy by 1.12 points (95% CI 0.41-1.83). No differences in 1-year mortality were observed. DISCUSSION: During the study period, high-income rural communities experienced more frequent and higher tier stroke center expansion than low-income rural communities. These access disparities were associated with differential gains in advanced stroke treatments, suggesting that expansions may have inadvertently widened income-based disparities in rural stroke care. These findings underscore the need for equity-focused implementation strategies, ensuring that infrastructure improvements translate into equitable clinical benefits.

Indexed as

CertificationHealth Services AccessibilityIncomeIschemic StrokeRural PopulationStrokeAgedAged, 80 and overFemaleHumansMaleMedicareRetrospective StudiesThrombectomyThrombolytic TherapyUnited States

Identifiers

PMID41576313
PMCPMC12834476

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.