Evidence map›Paper›PMID 41576166›Full record

ArticleScience advances2026

Resident CD49a

David Perea, Alba Gonzalez, Ana Gallego-Cortés, Nerea Sanchez-Gaona, Felix Pumarola, Nuria Ortiz, Ines Llano, Juan Lorente, Vicenç Falcó, Meritxell Genescà and 1 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David PereaHIV Translational Laboratory, Infectious Diseases Department, Vall d'Hebron Research Institute (VHIR), Autonomous University of Barcelona, 08035 Barcelona, Spain.ORCID 0000-0003-1562-4740
Alba GonzalezHIV Translational Laboratory, Infectious Diseases Department, Vall d'Hebron Research Institute (VHIR), Autonomous University of Barcelona, 08035 Barcelona, Spain.ORCID 0009-0006-0068-4352
Ana Gallego-CortésHIV Translational Laboratory, Infectious Diseases Department, Vall d'Hebron Research Institute (VHIR), Autonomous University of Barcelona, 08035 Barcelona, Spain.ORCID 0000-0001-5126-600X
Nerea Sanchez-GaonaHIV Translational Laboratory, Infectious Diseases Department, Vall d'Hebron Research Institute (VHIR), Autonomous University of Barcelona, 08035 Barcelona, Spain.ORCID 0000-0003-1977-8691
Felix PumarolaDepartment of Otorhinolaryngology, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.ORCID 0000-0002-7914-1695
Nuria OrtizDepartment of Otorhinolaryngology, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.ORCID 0009-0009-2939-7201
Ines LlanoDepartment of Otorhinolaryngology, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.
Juan LorenteDepartment of Otorhinolaryngology, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.ORCID 0000-0002-3264-0251
Vicenç FalcóInfectious Diseases Department, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.ORCID 0000-0001-9626-0023
Meritxell GenescàHIV Translational Laboratory, Infectious Diseases Department, Vall d'Hebron Research Institute (VHIR), Autonomous University of Barcelona, 08035 Barcelona, Spain.ORCID 0000-0001-6413-3812
Maria J BuzonHIV Translational Laboratory, Infectious Diseases Department, Vall d'Hebron Research Institute (VHIR), Autonomous University of Barcelona, 08035 Barcelona, Spain.ORCID 0000-0003-4427-9413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells are pivotal effectors in antiviral immunity, yet their tissue-specific roles during acute HIV infection remain poorly defined. Using an ex vivo human tonsillar tissue model, we profile NK cell responses to early HIV infection and uncover distinct subsets with specialized functions. We identify a previously uncharacterized memory-like NK population (CD16

Indexed as

Antigens, CDHIV InfectionsIntegrin alpha ChainsKiller Cells, NaturalLymphoid TissueNK Cell Lectin-Like Receptor Subfamily CCD4-Positive T-LymphocytesHIV-1HumansPalatine Tonsilalpha E integrinsAntigens, CDIntegrin alpha ChainsNK Cell Lectin-Like Receptor Subfamily C

Identifiers

PMID41576166
PMCPMC12829570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.