ArticleProceedings of the National Academy of Sciences of the United States of America2026
Neurochemical imaging reveals changes in dopamine dynamics with photoperiod in a seasonally social vole species.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Acute partner loss enhances social motivation and nucleus accumbens dopamine release in prairie voles.bioRxiv : the preprint server for biology · 2026Article
- Illuminating the Future of Catecholamine Detection.Journal of neurochemistry · 2026Review
- Adapting a Two-Photon Scanning Microscope for Simultaneous Single-Photon Imaging of an Infrared Dopamine Sensor.eNeuro · 2026Article
- Adapting a two-photon scanning microscope for simultaneous single-photon imaging of an infrared dopamine sensor.bioRxiv : the preprint server for biology · 2026Article
- Reunion with a peer partner reduces PVN oxytocin neuron immunoreactivity in socially selective voles.Scientific reports · 2025Article
- Oxytocin receptors mediate social selectivity in prairie vole peer relationships.Current biology : CB · 2025Article
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6 authors.
Funding
Abstract
Studying dopamine signaling in nonmodel organisms is crucial for understanding the broad range of behaviors not represented in traditional model systems. However, exploring new species is often hindered by a scarcity of tools suitable for nongenetic models. In this work, we introduce near-infrared catecholamine nanosensors (nIRCats) to investigate dopamine dynamics in meadow voles, a rodent species that exhibits distinct changes in social behavior and neurobiology across photoperiods. We observe increased dopamine release and release site density in voles housed in short photoperiods (which induce a social phenotype), suggesting adaptations linked to environmental changes. Moreover, pharmacological and extracellular manipulations demonstrate that short photoperiod/social voles exhibit heightened responsiveness to dopamine-increasing interventions and resilience against suppressive conditions. These findings highlight a significant association between dopamine signaling and photoperiod-driven changes in social behavior and establish nIRCats as an effective tool for expanding our understanding of dopamine dynamics across nonmodel organisms.
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Registered trials
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