Evidence map›Paper›PMID 41576006›Full record

ArticlePLOS global public health2026

Barriers to accessing high-quality cancer medicines in Cameroon. A qualitative study of the views and practices of regulators and frontline healthcare providers.

Yauba Saidu, Masong Christine Makia, Andreas Frambo, Armstrong Njuh Nang, Atalay Mulu, Ayenew Ashenef, Muluneh Benyam, Ibrahim Chikowe, Sonak D Pastakia, Colleen R Higgins and 2 more

Abstract read
In one paragraph

Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yauba SaiduClinton Health Access Initiative, Yaoundé, Cameroon.
Masong Christine MakiaDepartment of Social Sciences and Management, Catholic University of Central Africa, Yaoundé, Cameroon.ORCID https://orcid.org/0000-0002-2601-7068
Andreas FramboClinton Health Access Initiative, Yaoundé, Cameroon.ORCID https://orcid.org/0009-0001-5809-8800
Armstrong Njuh NangClinton Health Access Initiative, Yaoundé, Cameroon.ORCID https://orcid.org/0009-0007-1815-885X
Atalay MuluDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Ayenew AshenefDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0003-2505-899X
Muluneh BenyamDepartment of Pharmacy, University of North Carolina, Chapel Hill, United States of America.ORCID https://orcid.org/0000-0002-2387-6676
Ibrahim ChikoweDepartment of Pharmacy, Kamuzu University of Health Sciences, Blantyre, Malawi.
Sonak D PastakiaDepartment of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, United States of America.ORCID https://orcid.org/0000-0003-4259-695X
Colleen R HigginsDepartment of Pharmacy, University of North Carolina, Chapel Hill, United States of America.
Ndom PaulFaculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Marya LiebermanDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, United States of America.ORCID https://orcid.org/0000-0003-3968-8044

Funding

Point of use detection of low-quality pharmaceutical asparaginaseU01CA269195 · NCI · UNIVERSITY OF NOTRE DAME · PI Marya Lieberman · 2022 to 2026
$2.6M
NCI NIH HHS U01 CA269195
6 · The paper itself

Abstract

Cancer has become a major public health problem in Cameroon. In 2020, 20,000 new cases and 14,000 deaths were registered. Despite its high burden, access to quality medications for this condition continues to be a persistent challenge in the country. This study assessed the perceptions and practices of key stakeholders on barriers to accessing quality anticancer medicines in Cameroon. The overall goal was to generate data on key challenges related to the quality of anticancer medications and their impact on cancer care and treatment in Cameroon. This is to inform policy and interventions aimed at addressing the problem. In a cross-sectional qualitative study, a document review of key reports and documents, and 57 stakeholders were purposively identified and interviewed. The choice of these respondents was informed by their engagements in one of the areas of the chemotherapy supply chain in Cameroon, including regulation, procurement, quality control, and use. Data from document notes and interviews were analyzed using a thematic approach. Several factors were identified as affecting the quality of chemotherapy medications, including weak regulatory systems, inadequate funding for regulatory activities, and a lack of core competencies among staff responsible for regulatory functions. Other factors included the high cost of anticancer medications, which influenced accessibility to quality products, as well as the quality of care offered to patients who could not afford high-priced products. These weaknesses, coupled with a lack of point-of-care tools, appear to encourage the proliferation of substandard medicines in our setting and the use of substandard therapies or protocols to treat patients. Our study sheds light on the multifaceted problems that plague Cameroon's chemotherapy supply chain and how these impact access to optimal care and treatment for cancer patients. Urgent actions are needed to enhance the regulatory landscape and improve the affordability of quality anticancer medications in Cameroon.

Identifiers

PMID41576006
PMCPMC12829877

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.