Evidence map›Paper›PMID 41575862›Full record

ArticleJMIR rehabilitation and assistive technologies2026

Therapeutic Use of Virtual Reality for Patients With Fibromyalgia and Chronic Neck Pain: Randomized Controlled Trial.

Edurne Úbeda-D'Ocasar, Yaiza Moreno-Crespo, Eduardo Cimadevilla-Fernández-Pola, Juan Hernández-Lougedo, Álvaro Navas-Mosqueda, Mario Caballero-Corella, Noemí Mayoral-Gonzalo, Blanca Pedauyé-Rueda, María Jesús Fernández-Aceñero, Juan Pablo Hervás-Pérez and 1 more

Abstract read
In one paragraph

Article in JMIR rehabilitation and assistive technologies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Edurne Úbeda-D'Ocasar *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0000-0003-4419-8613
Yaiza Moreno-Crespo *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0009-0003-0113-8175
Eduardo Cimadevilla-Fernández-Pola *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0000-0002-8168-2845
Juan Hernández-Lougedo *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0000-0002-3302-4346
Álvaro Navas-Mosqueda *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0000-0002-2176-9105
Mario Caballero-Corella *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0000-0002-9895-7331
Noemí Mayoral-Gonzalo *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0000-0001-8902-8939
Blanca Pedauyé-Rueda *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0009-0004-6504-7691
María Jesús Fernández-Aceñero *Department of Legal Medicine, Psychiatry and Pathology, Facultad de Medicina, Universidad Complutense de Madrid, Fundación de Investigación Clínico San Carlos (IDiSCC), Madrid, Spain.ORCID http://orcid.org/0000-0002-2439-3553
Juan Pablo Hervás-Pérez *Department of Chemistry in Pharmaceutical Sciences, Analytical Chemistry Unit, Faculty of Pharmacy, Complutense University of Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, Madrid, Spain, +34 918153131.ORCID http://orcid.org/0000-0003-3234-0993
Cristina Ojedo-Martín *Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, Camilo José Cela University, Villanueva de la Cañada, Madrid, 28692, Spain.ORCID http://orcid.org/0000-0003-3697-7051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fibromyalgia (FM) causes widespread pain, fatigue, and cognitive abnormalities. Cervical pain is a common and debilitating symptom. Objective: This study aims to evaluate the effectiveness of virtual reality (VR) as a treatment for chronic cervical pain experienced by patients with FM. Methods: A single-blind randomized clinical trial was conducted. A total of 56 women were randomly assigned to 3 groups: G1 (VR+cervical mobility exercises), G2 (cervical mobility exercises), and the control group. Therapy was administered twice a week for 4 weeks. Variables such as disease impact, quality of life, kinesiophobia, pain, range of motion, fatigue, and treatment adherence were measured. Results: The mean age of the participants was 54.26 (SD 7.7) years. Participants were overweight, with a mean BMI of 28.7 (SD 7.8). The mean visual analog scale value was 6.72 (SD 1.8). The baseline values for age, BMI, visual analog scale, algometric measures, and functional capacity (measured using the Timed Up and Go test, cervical rotation, and lateral displacement) were similar across the 3 groups. Following the intervention therapy, the control group did not exhibit notable improvement (mean 3.5, SD 1.4; differences of mean values -0.46, 95% CI -1.1 to 0.2; P=.15), particularly in pain perception, while both therapy groups did show improvements (G1: mean 3.8, SD 1.1; differences of mean values 1.2, 95% CI 0.78-1.54; P<.001; G2: mean 2.8, SD 1.8; differences of mean values 1.2, 95% CI 0.66-1.7; P<.001). Both intervention groups improved significantly compared to control postintervention in FM impact (CG vs G1: differences of mean values 9.31, 95% CI 14.7-3.8; P<.001; CG vs G2: differences of mean values 8.4, 95% CI 13.84-3.06; P<.001), central sensitization (CG vs G2: differences of mean values 7.53, 95% CI 12.12-2.95; P<.001), and cervical disability (CG vs G2: differences of mean values 6.44, 95% CI 9.93-2.94; P<.001). However, at 1 month, only G1 maintained superior improvements across all measures, including a reduction in kinesiophobia (G2: differences of mean values 6.2, 95% CI 4.7-9.8; P<.001), indicating a more sustained effect of the combined approach. Conclusions: The combination of VR with cervical mobility and strengthening exercises produced superior and sustained improvements in women with FM compared to exercise alone or control. Significant benefits were observed in disease impact, central sensitization, cervical disability, and kinesiophobia, with effects maintained at 1 month only in the VR group. These findings support VR as an effective adjunct to enhance symptom management and treatment adherence in FM.

Indexed as

chronic neck painexercisefibromyalgiarandomized controlled trialvirtual reality

Identifiers

PMID41575862
PMCPMC12829586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.