ArticleJournal of the American Chemical Society2026
Catalytic Stereospecific Construction of Aminocyclopropanes from β-Boryl Amides.
Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Stereospecific Epoxide-to-Cyclopropylamine Conversion by a Homologous Horner-Wadsworth-Emmons-Type Reaction With an Imine-Substituted Phosphine Oxide.Angewandte Chemie (International ed. in English) · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
Abstract
Iridium-catalyzed reduction of β-boryl amides with tetramethyldisiloxane affords iminium ions in situ. These reactive iminium ions are directly trapped by stereospecific (invertive) reaction with the boronate, delivering aminocyclopropanes (ACPs) in excellent yield, diastereoselectivity, and enantiospecificity. The reaction applies to both secondary and tertiary benzylic boronates, allylic boronates, and α-substituted boronates, giving access to many multiply substituted ACPs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.