Evidence map›Paper›PMID 41575696›Full record

Observational studyInternational ophthalmology2026

Mucus fishing syndrome: clinical spectrum and update on its multifactorial pathogenic mechanisms.

Gustavo Ortiz-Morales, Raúl Hernán Barceló-Cantón, Enrique O Graue-Hernandez, Alejandro Rodriguez-Garcia

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gustavo Ortiz-MoralesTecnologico de Monterrey, School of Medicine and Health Sciences, Institute of Ophthalmology and Visual Sciences, Av. Batallon de San Patricio No. 112. Col Real de San Agustín., Monterrey, 66278, Mexico.ORCID http://orcid.org/0000-0003-4217-8985
Raúl Hernán Barceló-CantónTecnologico de Monterrey, School of Medicine and Health Sciences, Institute of Ophthalmology and Visual Sciences, Av. Batallon de San Patricio No. 112. Col Real de San Agustín., Monterrey, 66278, Mexico.ORCID http://orcid.org/0009-0003-6757-819X
Enrique O Graue-HernandezInstituto de Oftalmologia Fundacion Conde de Valenciana IAP., Mexico City, Mexico.ORCID http://orcid.org/0000-0003-3267-3915
Alejandro Rodriguez-GarciaTecnologico de Monterrey, School of Medicine and Health Sciences, Institute of Ophthalmology and Visual Sciences, Av. Batallon de San Patricio No. 112. Col Real de San Agustín., Monterrey, 66278, Mexico. immuneye@gmail.com.ORCID http://orcid.org/0000-0002-1419-2109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze the clinical spectrum of mucus-fishing syndrome (MFS), an often-overlooked cause of dry eye disease, marked by a vicious cycle of self-induced ocular surface irritation and mucus overproduction.

methodsRetrospective observational case series study.

resultsA total of 29 patients with MFS were included. Most patients were female (89.6%) with a mean age of 54.3 ± 18.5 years. Psychological and psychiatric comorbidities were reported in 31.0% of the patients, with anxiety and depression being the most common. Patients primarily used their fingernails (82.7%) for filament removal, along with other methods including cotton swabs, paper tissues, and needles. Common symptoms included an imminent feeling of mucus removal (100%), foreign body sensation (96.5%), tearing (51.7%), and a red eye (41.3%). Treatment focused on patient education, ocular surface management, and adjuvant therapies, achieving favorable responses in 55.1% of the patients within the first month.

conclusionMFS is an insidious cause of dry eye syndrome that may be underdiagnosed because of patient embarrassment and limited clinician awareness. Effective management requires patient education to avoid filament removal and to address the underlying ocular and mental health conditions.

Indexed as

Dry Eye SyndromesMucusTearsAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSyndromeChronic conjunctivitisDry eye syndromeFilamentary keratitisKeratoconjunctivitisMucinsMucus fishing syndrome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.