Evidence map›Paper›PMID 41575593›Full record

ArticleWorld journal of urology2026

P.I. nomogram: an exploratory imaging-derived model for predicting early urinary incontinence following ThuLEP.

Xiao-Da Lan, Rui Jiang, He Wang, Yelin Mulati, Kai Zhang, Qian Zhang, Jingyun Wu, YiSen Meng, Yi-Sen Meng

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Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xiao-Da Lan *Department of Urology, Institute of Urology, National Research Center for Genitourinary Oncology, Peking University First Hospital, Peking University, Beijing, 100034, China.
Rui Jiang *Department of Urology, Institute of Urology, National Research Center for Genitourinary Oncology, Peking University First Hospital, Peking University, Beijing, 100034, China.
He WangDepartment of Radiology, Peking University First Hospital, Peking University, Beijing, 100034, China.
Yelin MulatiDepartment of Urology, Institute of Urology, National Research Center for Genitourinary Oncology, Peking University First Hospital, Peking University, Beijing, 100034, China.
Kai ZhangDepartment of Urology, Institute of Urology, National Research Center for Genitourinary Oncology, Peking University First Hospital, Peking University, Beijing, 100034, China.
Qian ZhangDepartment of Urology, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, China.
Jingyun WuDepartment of Radiology, Peking University First Hospital, Peking University, Beijing, 100034, China. wujingyun1129@163.com.
YiSen MengDepartment of Urology, Institute of Urology, National Research Center for Genitourinary Oncology, Peking University First Hospital, Peking University, Beijing, 100034, China.
Yi-Sen MengDepartment of Urology, Institute of Urology, National Research Center for Genitourinary Oncology, Peking University First Hospital, Peking University, Beijing, 100034, China. mgyss@aliyun.com.

Funding

Clinical Research Program for Researching Hospital Wards BRWEP2024W054070103National High Level Hospital Clinical Research Funding 2024IR16Natural Science Foundation of Ningxia Hui Autonomous Region 2024AAC03738Teaching Project at the Hospital Level of Peking University First Hospital 2024YJ23
6 · The paper itself

Abstract

backgroundEarly postoperative urinary incontinence (UI) after thulium laser enucleation of the prostate (ThuLEP) can significantly affect postoperative quality of life. Predictive models for UI following ThuLEP are currently lacking. Prostatic apex shape (PAS), initially proposed in prostate cancer research, has shown value in predicting surgical outcomes but remains underexplored in benign prostatic hyperplasia (BPH). This study aimed to develop a nomogram based on PAS and clinical parameters to provide a noninvasive estimate of short-term UI risk after ThuLEP.

methodsPatients who underwent ThuLEP for BPH at a high-volume center were retrospectively included. Inclusion criteria were preoperative BPH diagnosis, mpMRI examination, and complete follow-up data. PAS was classified into four subtypes (A, B, C, D) using a modified MRI-based method. Clinical variables, including intravesical prostatic protrusion (IPP), were collected. Logistic regression analysis was used to identify independent predictors of early postoperative UI, and a nomogram was developed and evaluated using the area under the curve (AUC), calibration analysis, and decision curve analysis.

resultsA total of 106 patients were included. Early postoperative UI at 1 month occurred in 40 patients (37.7%), with type D showing a significantly lower incidence (p = 0.029). On univariable analysis, PAS (A-C vs. D), IPP > 2.4 cm, and PV > 100 mL were associated with UI. In multivariable models, PAS types A-C (OR 11.721, 95% CI 1.431-85.996; p = 0.022) and IPP > 2.4 cm (OR 11.543, 95% CI 1.350-74.322; p = 0.026) remained independent predictors. P.I. nomogram (PAS, IPP) achieved an AUC of 0.758, demonstrated good calibration (Hosmer-Lemeshow P = 0.993), and showed greater net benefit particularly at threshold probabilities 0.4-0.6.

conclusionPAS types A-C and IPP > 2.4 cm were independently associated with 1-month postoperative urinary incontinence after ThuLEP. Our P.I. nomogram showed acceptable discrimination and calibration for short-term UI risk in this exploratory cohort. If confirmed in external populations, this tool may assist preoperative risk stratification and counselling in patients undergoing ThuLEP.

Indexed as

Laser TherapyNomogramsPostoperative ComplicationsProstateProstatectomyProstatic HyperplasiaUrinary IncontinenceAgedHumansMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsRetrospective StudiesThuliumTime FactorsThuliumEndoscopic surgical proceduresLaser therapyProstatic hyperplasiaUrinary incontinence

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.