Evidence map›Paper›PMID 41575540›Full record

Observational studyActa orthopaedica2026

The risk of revision using tourniquet or not in primary total knee replacement: an observational study from the Swedish Knee Arthroplasty Register.

Annette W-Dahl, Johan Kärrholm, Perna Ighani Arani, Ola Rolfson

Abstract readObservational Study
In one paragraph

Observational study in Acta orthopaedica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Annette W-DahlThe Swedish Arthroplasty Register; Department of Clinical Sciences Lund, Division of Orthopedics, Lund University, Lund, Sweden. annette.w-dahl@med.lu.se.ORCID 0000-0003-4053-7358
Johan KärrholmThe Swedish Arthroplasty Register; Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-4782-7999
Perna Ighani AraniThe Swedish Arthroplasty Register; Faculty of Medicine and Health, School of Medical Sciences, Örebro University, Örebro, Sweden.
Ola RolfsonThe Swedish Arthroplasty Register; Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-6534-1242

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe use of a tourniquet in knee replacement surgery is debated. Given the conflicting evidence, we aimed to compare the risk of revision after total knee replacements (TKR) with or without the use of tourniquet.

methodsIn this register based observational study, we included the 5 most common cemented primary TKR models due to osteoarthritis reported to the Swedish Arthroplasty Register 2010-2024 and followed them until December 31, 2024. The first revision for implant loosening was the primary outcome. We estimated the cumulative revision rate (CRR) with 95% confidence interval (CI) using the 1-Kaplan-Meier method. We examined the use of a tourniquet regarding the risk of revision using multiple Cox regression analysis to calculate the hazard ratio (HR) with CI and adjusted for potential confounding factors.

resultsOf the 149,616 TKRs included, 65,570 (44%) were with tourniquet and 84,046 (56%) without tourniquet. The CRR was similar at all time-points for all causes and infection; however, CRR started to increase at 6-7 years for implant loosening with use of a tourniquet. In the Cox regression analysis, the use of a. tourniquet was associated with an increased risk of revision for implant loosening after 5 years (HR 1.56, CI 1.06-2.30). There was no difference in revision for all causes (HR 1.07, CI 0.99-1.15) or infection (HR 1.08, CI 0.97-1.21).

conclusionThe use of a tourniquet was associated with an increased risk of revision for implant loosening after 5 years, while no association was found for all-cause revision or infection. Our results do not support the use of a tourniquet in TKR as a strategy to reduce the risk of revision, either due to all causes, implant loosening, or infection.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeProsthesis FailureReoperationTourniquetsAgedAged, 80 and overFemaleHumansMaleMiddle AgedRegistriesRisk FactorsSweden

Identifiers

PMID41575540
PMCPMC12831073

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.