Evidence map›Paper›PMID 41575370›Full record

ArticleAlcohol, clinical & experimental research2026

The influence of alcohol on prehospital diagnostics and therapy of injured patients.

Ramona Sturm, Jason-Alexander Hörauf, Rolf Lefering, Borna Relja, Ingo Marzi, Nils Wagner, TraumaRegister DGU

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ramona SturmDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe-University Frankfurt, Frankfurt am Main, Germany.ORCID https://orcid.org/0009-0009-7544-9770
Jason-Alexander HöraufDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Rolf LeferingInstitute for Research in Operative Medicine (IFOM), University Witten/Herdecke, Cologne, Germany.
Borna ReljaDepartment of Orthopedic Trauma, Hand-, Plastic-, and Reconstructive Surgery, Translational and Experimental Trauma Research, University Ulm, Ulm, Germany.
Ingo MarziDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Nils WagnerDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe-University Frankfurt, Frankfurt am Main, Germany.
TraumaRegister DGUCommittee on Emergency Medicine, Intensive Care and Trauma Management (NIS) of the German Trauma Society (DGU), Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prehospital assessment and subsequent therapeutic interventions are crucial for the optimal management of severely injured patients. Many trauma patients are alcohol-intoxicated. Therefore, this study investigated the prehospital assessment of the injury pattern and management of alcohol-intoxicated patients.

methodsIn a retrospective matched-pair analysis of TraumaRegister DGU® data patients from 2015 to 2018 with a blood alcohol level (BAL+) > 1.0‰ and without a blood alcohol level (BAL-: 0.0‰) were investigated, matched by age, gender, injured region, and mechanism. We evaluated injury assessment, prehospital therapy, and transport modalities.

resultsA total of 6468 patients (3234 BAL-, 3234 BAL+) were included. Head injuries were common (56.9%), but BAL+ patients were significantly less often correctly assessed with regard to head (BAL-: 77.8% vs. BAL+: 74.2%) and facial (BAL-: 75.4% vs. BAL+: 70.0%, p < 0.001) injuries. Head and facial injuries were significantly more often improperly overdiagnosed in alcohol-intoxicated patients (head: BAL-: 13.9% vs. BAL+: 21.4%, p < 0.05; face: BAL-: 19.8% vs. BAL+: 24.3%, p < 0.001), and the diagnosis of actual head injuries was underdiagnosed significantly more often in patients with BAL+. Alcohol-intoxicated patients were sedated (BAL-: 64.9% vs. BAL+: 55.6%, p < 0.001) and intubated (BAL-: 39.0% vs. BAL+: 28.3%, p < 0.001) significantly less often and received significantly less fluid therapy (BAL-: 92.6% vs. BAL+: 90.3%, p < 0.001), catecholamines (BAL-: 12.7% vs. BAL+: 8.5%, p < 0.001), or tranexamic acid (BAL-: 10.3% vs. BAL+: 6.3%, p < 0.001). Admission of alcohol-intoxicated patients to hospital was significantly more frequent at weekends and at night, and more frequent in regional and local trauma centers than in supraregional trauma centers.

conclusionsThere were significant differences in the prehospital assessment of head injuries between alcohol-intoxicated and nonalcohol-intoxicated patients. Alcohol-intoxicated patients were significantly less often correctly assessed, and alcohol-intoxicated patients received fewer prehospital therapeutic interventions.

Indexed as

Alcoholic IntoxicationCraniocerebral TraumaEmergency Medical ServicesEthanolWounds and InjuriesAdultAgedBlood Alcohol ContentFacial InjuriesFemaleHumansMaleMiddle AgedRegistriesRetrospective StudiesYoung AdultBlood Alcohol ContentEthanolalcoholinjury severityprehospital treatmenttrauma patients

Identifiers

PMID41575370
PMCPMC12829515

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.