ArticleAnnals of African medicine2026
Acute Cerebellitis: A Rare Complication of Scrub Typhus.
Article in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
abstractScrub typhus, caused by Orientia tsutsugamushi , is an emerging zoonotic infection that typically presents as an acute febrile illness. While neurological manifestations are increasingly recognized, cerebellar involvement remains exceedingly rare. We report the case of a 42-year-old man from Uttar Pradesh who presented with high-grade fever, followed by slurred speech and gait ataxia. Clinical examination revealed cerebellar signs, including dysmetria and dysdiadochokinesia. Laboratory testing confirmed scrub typhus via a positive immunoglobulin M enzyme-linked immunosorbent assay, and other infectious and autoimmune etiologies were excluded. Magnetic resonance imaging of the brain and cerebrospinal fluid analysis were normal. The patient was treated successfully with intravenous doxycycline and methylprednisolone, resulting in rapid clinical improvement. This case highlights acute cerebellitis as an atypical but important complication of scrub typhus, underscoring the need for heightened clinical suspicion in endemic areas.
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