SynthesisMedical gas research2026
Hyperbaric oxygen therapy and Fournier's gangrene: a systematic review and meta-analysis.
Synthesis in Medical gas research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Hyperbaric Oxygen Therapy Is Associated with Lower Mortality in Patients with Fournier's Gangrene: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fournier's gangrene is a rare, rapidly progressive necrotizing soft tissue infection of the genitals and perineum that continues to carry a high mortality rate. Hyperbaric oxygen therapy has been proposed as an adjunctive treatment, but its efficacy remains uncertain. We conducted a systematic review and meta-analysis of studies comparing hyperbaric oxygen therapy with standard care in adults with Fournier's gangrene. A comprehensive search of PubMed/MEDLINE, Embase, Cochrane Library, Scopus, and Web of Science identified 13 retrospective studies including 322 patients treated with hyperbaric oxygen therapy and 366 controls. Hyperbaric oxygen therapy was associated with a significantly lower mortality rate compared with control groups. Secondary outcomes, including hospital length of stay and number of debridements, showed inconsistent results and did not differ significantly between groups. These findings suggest that hyperbaric oxygen therapy may reduce mortality in patients with Fournier's gangrene and could be considered as an adjunctive therapy.
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