Article in American journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors.
Joanna L ClasenHealth Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.ORCID 0000-0003-4231-5740
Berglind JonsdottirDepartment of Pediatrics, The Children's Hospital Iceland, Reykjavik, Iceland.ORCID 0000-0003-4129-1767
Kendra VehikHealth Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.ORCID 0000-0001-6243-6772
Kristian F LynchHealth Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.ORCID 0000-0002-4310-4163
Hemang M ParikhHealth Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.ORCID 0000-0002-9076-6709
Jaakko J KoskenniemiDepartment of Pediatrics, Turku University Hospital, Turku, Finland.ORCID 0000-0002-9348-3325
Daniel AgardhUnit of Celiac Disease and Diabetes, Clinical Sciences Malmö, Lund University, Lund, Sweden.ORCID 0000-0003-1435-1234
William A HagopianDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, United States.ORCID 0000-0003-2979-0475
Marian J RewersBarbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO, United States.ORCID 0000-0003-3829-9207
Jorma ToppariDepartment of Pediatrics, Turku University Hospital, Turku, Finland.ORCID 0000-0003-2228-334X
Anette-Gabriele ZieglerInstitute of Diabetes Research, Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.ORCID 0000-0002-6290-5548
Beena AkolkarNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, United States.ORCID 0000-0002-2351-5942
Jeffrey P KrischerHealth Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.ORCID 0000-0003-4526-888X
Michael HallerDepartment of Pediatrics, Diabetes Institute, College of Medicine, University of Florida, Gainesville, FL, United States.ORCID 0000-0002-2803-1824
Helena Elding LarssonDepartment of Clinical Sciences Malmö, Lund University, Lund, Sweden.ORCID 0000-0003-3306-1742
Funding
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)U01DK128847 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI JEFFREY P KRISCHER · 2021 to 2026
$79.2M
Data Coordinating Center (DCC)for the Consortium for Identification of EnvironmenUC4DK095300 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2011 to 2011
$56.0M
NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Data Coordinating CenterU01DK063790 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2002 to 2006
$50.1M
Follow-up on Subjects, Integrative Data Analysis and Measurement of Viral Antibodies in The Environmental Determinants of Diabetes in The Young Study (TEDDY)U01DK124166 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2020 to 2022
$31.1M
NIDDK Follow-up on Subjects and Immunological Assessments in The Environmental Determinants of Diabetes In The Young Study (TEDDY) (UC4)UC4DK117483 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2017 to 2020
$30.4M
Establish a Data Coordinating Center (DCC) for the Consortium for Identification UC4DK100238 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2014 to 2014
$28.9M
The Study of Epigenetics and Infections in The Environmental Determinants of Diabetes in the Young (TEDDY)UC4DK112243 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2016 to 2016
$27.0M
Data Coordinating Center (DCC) for the Consortium for Identification of Environmental Determinants of Diabetes in the Young (TEDDY) StudyUC4DK106955 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2015 to 2015
$20.0M
The Environmental Determinants of Diabetes in Young (TEDDY0U01DK063863 · NIDDK · HOSPITAL DISTRICT OF SOUTHWEST FINLAND · PI TOPPARI, JORMA · 2003 to 2022
$13.5M
The Environmental Triggers of Diabetes (TEDDY) in SwedenU01DK063861 · NIDDK · UNIVERSITY OF WASHINGTON · PI LERNMARK, AKE · 2003 to 2022
$13.4M
THE TEDDY STUDY - COLORADO CLINICAL CENTERU01DK063821 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J · 2003 to 2022
$12.3M
Breakthrough T1D (formerly JDRF)Centers for Disease Control and Prevention (CDC)Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)National Institute of Allergy and Infectious Diseases (NIAID)National Institute of Environmental Health Sciences (NIEHS)NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR002535NIDDK NIH HHS U01 DK063790NIDDK NIH HHS U01 DK063821NIDDK NIH HHS U01 DK063829NIDDK NIH HHS U01 DK063836NIDDK NIH HHS U01 DK063861NIDDK NIH HHS U01 DK063863NIDDK NIH HHS U01 DK063865NIDDK NIH HHS U01 DK124166NIDDK NIH HHS U01 DK128847NIDDK NIH HHS UC4 DK063821NIDDK NIH HHS UC4 DK063829NIDDK NIH HHS UC4 DK063836NIDDK NIH HHS UC4 DK063861NIDDK NIH HHS UC4 DK063863NIDDK NIH HHS UC4 DK063865NIDDK NIH HHS UC4 DK095300NIDDK NIH HHS UC4 DK100238NIDDK NIH HHS UC4 DK106955NIDDK NIH HHS UC4 DK112243NIDDK NIH HHS UC4 DK117483NIH/NCATS Clinical and Translational Science Awards to the University of Florida UL1 TR000064NLM NIH HHS HHSN267200700014Cthe National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)the University of Colorado UL1 TR002535
6 · The paper itself
Abstract
We aimed to determine if thyroid autoimmunity is associated with a child's risk for subsequent development of islet or celiac autoantibodies. Children at high genetic risk of type 1 diabetes were followed for thyroid autoimmunity (thyroid peroxidase antibodies [TPOAb] and thyroglobulin antibodies [TGAb]), islet autoimmunity (IA), and celiac disease autoimmunity (CDA) in The Environmental Determinants of Diabetes in the Young study. Out of 5482 children tested for thyroid autoimmunity, IA, and CDA, 39% developed at least one autoantibody. At age 14 years, thyroid autoimmunity co-occurred with IA in 59 children (15 more cases than expected by chance alone, P = 0.02) and with CDA in 125 children (26 cases above expected, P = 0.01). The risk of developing IA or CDA after thyroid autoimmunity varied by which thyroid autoantibody appeared first: TPOAb-first was associated with both IA (HR 1.92, 95% CI, 1.09-3.40) and CDA (1.69, 95% CI, 1.03-2.76), whereas TGAb-first was not associated with the risk of either. Islet autoimmunity and CDA are frequently found in connection to thyroid autoimmunity in children and young adolescents. The relationships of thyroid autoimmunity with IA and CDA depend on which thyroid autoantibody appears first.
Indexed as
AutoantibodiesAutoimmunityCeliac DiseaseDiabetes Mellitus, Type 1Islets of LangerhansThyroid GlandThyroiditis, AutoimmuneAdolescentChildChild, PreschoolFemaleHumansIodide PeroxidaseMaleAutoantibodiesIodide Peroxidasecomorbidityislet autoantibodieslongitudinal datathyroid autoantibodiestissue transglutaminase autoantibodies
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Thyroid autoimmunity and the subsequent development of islet and celiac autoimmunity in the TEDDY study. · full record | OpenQuestion