SynthesisWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Plain Radiography for Diagnosing and Monitoring Foot Osteomyelitis in Persons With Diabetes: Accuracy, Limitations and Clinical Utility.
Synthesis in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Plain Radiography for Diagnosing and Monitoring Foot Osteomyelitis in Persons With Diabetes: Accuracy, Limitations and Clinical Utility.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyPooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteomyelitis of the feet is common in persons living with diabetes due to peripheral artery disease, peripheral neuropathy, and increased susceptibility to infection. Although plain radiography is a low-cost and widely available diagnostic tool, its diagnostic performance is limited. Serial radiography may improve the accuracy and clinical utility. This systematic review studies the diagnostic accuracy, limitations, and clinical utility of singular versus serial plain radiography for diagnosing osteomyelitis in the foot in persons with diabetes at diagnosis and follow-up. We conducted PubMed and Embase searches for articles on the diagnostic performance of serial plain radiography for osteomyelitis of the foot in patients with diabetes. Multiple z-tests were used to compare the performance of singular and serial radiographs. Fourteen studies were included, with only one providing original data on serial radiography. The sensitivity of singular radiography ranged from 22% to 93%, and specificity ranged from 22% to 94%. Serial radiography had a sensitivity of 89% and a specificity of 38%. Of the 13 studies, serial radiography outperformed singular radiography in terms of sensitivity in three reports but failed to outperform singular radiography on specificity in any of the reports. The initial examination indicated little advantage of serial radiography over singular radiography for the diagnosis of diabetic foot osteomyelitis. However, a significant exclusion bias exists due to the lack of research in this area. Further research is warranted to clarify the clinical utility of serial radiography.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.