Evidence map›Paper›PMID 41574350›Full record

ArticlePulmonary circulation2026

Refractory Peripheral Pulmonary Stenosis and Severe Pulmonary Arterial Hypertension Associated With a

Lea C Steffes, Gregory T Adamson, Kyla E Dunn, Jeffrey A Feinstein

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lea C SteffesDepartment of Pediatrics, Division of Pediatric Pulmonology, Lucile Salter Packard Children's Hospital Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0000-0002-1592-4025
Gregory T AdamsonDepartment of Pediatrics, Division of Pediatric Cardiology, Lucile Salter Packard Children's Hospital Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0000-0003-4313-0983
Kyla E DunnPediatric Inherited Cardiovascular Disorders Program, Children's Heart Center, Stanford Medicine Children's Health; Stanford Center for Inherited Cardiovascular Disease Stanford University School of Medicine Palo Alto California USA.
Jeffrey A FeinsteinDepartment of Pediatrics, Division of Pediatric Cardiology, Lucile Salter Packard Children's Hospital Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0000-0002-6078-5976

Funding

Exploiting neointimal and vascular smooth muscle cell heterogeneity to reveal mechanisms driving venous neointimal growth and vascular remodeling in pediatric pulmonary hypertensionK08HL173632 · NHLBI · STANFORD UNIVERSITY · PI Lea Steffes · 2024 to 2026
$496k
NHLBI NIH HHS K08 HL173632
6 · The paper itself

Abstract

We report a novel genetic variant in a patient with treatment-resistant peripheral pulmonary artery stenosis (PPS) and progressive pulmonary arterial hypertension (PAH). A premature infant was diagnosed with bilateral PPS requiring multiple surgical reconstructions and interventional procedures with refractory proximal stenoses. Despite adequate anatomic repair preserving nearly all right lung segments, the child developed progressive PAH with elevated pressures in preserved segments out of proportion to residual obstruction. Genetic evaluation revealed a

Identifiers

PMID41574350
PMCPMC12821213

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.