Evidence map›Paper›PMID 41574337›Full record

ArticleFrontiers in microbiology2025

Assessment of the phi6 lysis system using genetic complementation and heterologous expression in

Devyn Del Curto, Micaela Zamora, Greyson Lasley, Rabia Khan, Katlyn Montalbano, J Bryce Ricken, Jesse Cahill

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Devyn Del CurtoEnvironmental Systems Biology, Sandia National Labs, Albuquerque, NM, United States.
Micaela ZamoraEnvironmental Systems Biology, Sandia National Labs, Albuquerque, NM, United States.
Greyson LasleyEnvironmental Systems Biology, Sandia National Labs, Albuquerque, NM, United States.
Rabia KhanEnvironmental Systems Biology, Sandia National Labs, Albuquerque, NM, United States.
Katlyn MontalbanoEnvironmental Systems Biology, Sandia National Labs, Albuquerque, NM, United States.
J Bryce RickenEnvironmental Systems Biology, Sandia National Labs, Albuquerque, NM, United States.
Jesse CahillEnvironmental Systems Biology, Sandia National Labs, Albuquerque, NM, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The RNA cystovirus phi6 represents a unique evolutionary outlier, encoding a holin and endolysin similar to tailed phages, yet lacking an identified gene for outer membrane disruption. In this study, we investigated the phi6 lysis system using genetic complementation experiments and heterologous expression in

Indexed as

cystoviridaedisruptinholinouter membrane disruptorP10P5spanin

Identifiers

PMID41574337
PMCPMC12819732

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.