Evidence map›Paper›PMID 41574308›Full record

ArticleACS applied nano materials2025

Time-Resolved Förster Resonance Energy Transfer Nanoassay Based on CdTe Quantum Dots for Sensitive Detection of Prostate Cancer Antigen 3.

Catarina S M Martins, Anne Nsubuga, Nour Fayad, Ruifang Su, Thibault Gallavardin, Ihsan Çaha, Niko Hildebrandt, Francis Leonard Deepak, João A V Prior

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In one paragraph

Article in ACS applied nano materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catarina S M MartinsLAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy of the University of Porto, Porto 4050-313, Portugal.ORCID https://orcid.org/0000-0001-9222-2556
Anne NsubugaLaboratoire COBRA, Université de Rouen Normandie, CNRS, INSA, Rouen 76821, France.
Nour FayadLaboratoire COBRA, Université de Rouen Normandie, CNRS, INSA, Rouen 76821, France.
Ruifang SuLaboratory of Biomaging and Pathologies, UMR 7021 CNRS, University of Strasbourg, Strasbourg 67000, France.ORCID https://orcid.org/0000-0003-3328-0136
Thibault GallavardinLaboratoire COBRA, Université de Rouen Normandie, CNRS, INSA, Rouen 76821, France.
Ihsan ÇahaInternational Iberian Nanotechnology Laboratory, Braga 4715-330, Portugal.ORCID https://orcid.org/0000-0002-8212-874X
Niko HildebrandtMcMaster University, Department of Engineering Physics, Hamilton L8S 4L7, Canada.ORCID https://orcid.org/0000-0001-8767-9623
Francis Leonard DeepakInternational Iberian Nanotechnology Laboratory, Braga 4715-330, Portugal.ORCID https://orcid.org/0000-0002-3833-1775
João A V PriorLAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy of the University of Porto, Porto 4050-313, Portugal.ORCID https://orcid.org/0000-0002-6961-345X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate Cancer Antigen 3 (PCA3) is a long noncoding RNA highly expressed in prostate cancer cells, making it a promising biomarker for noninvasive prostate cancer diagnosis. Simple and rapid detection using nanoprobes can potentially overcome the limitations of traditional diagnostic techniques. Here, we designed, characterized, and applied a DNA-strand displacement assay based on Förster Resonance Energy Transfer (FRET) between terbium (Tb) ions and semiconductor quantum dots (QDs) as a proof-of-concept for sensitive and specific mix-and-measure quantification of a synthetic DNA analogue of PCA3. The assay utilized QDs synthesized through an aqueous one-pot method. The time-resolved (TR) FRET assays achieved a detection limit of 0.65 nmol L

Indexed as

diagnosticslncRNAPCA3quantum dotsterbiumTR-FRET

Identifiers

PMID41574308
PMCPMC12821037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.