Evidence map›Paper›PMID 41574307›Full record

ArticleFrontiers in cellular and infection microbiology2025

Opposing fates: a bipolar cellular model for FMDV replication shaped by

Xiangdong Song, Yan Cui, Fanglan An, Yajun Li, Jianping Liang, Shiyu Tao, Xuerong Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiangdong SongCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu, China.
Yan CuiCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu, China.
Fanglan AnChina Agricultural Vet Biology and Technology Co., Ltd, Lanzhou, Gansu, China.
Yajun LiChina Agricultural Vet Biology and Technology Co., Ltd, Lanzhou, Gansu, China.
Jianping LiangInstitute of Modern Physics (IMP), Chinese Academy of Sciences, Lanzhou, Gansu, China.
Shiyu TaoGansu Normal University for Nationalities, Hezuo, Gansu, China.
Xuerong LiuChina Agricultural Vet Biology and Technology Co., Ltd, Lanzhou, Gansu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: By pioneering the use of an 80 MeV/u Methods: This approach yielded two distinct clones: a highly antiviral line (BHK-5) and a highly proviral line (BHK-7). Multi-omics analyses were employed to investigate the mechanisms driving these divergent phenotypes. Results: The divergent phenotypes stem from a profound reprogramming of host transcriptional networks. The antiviral BHK-5 clone exhibits a pre-activated innate immune state, leveraging Discussion: Our work demonstrates that

Indexed as

Foot-and-Mouth Disease VirusMutagenesisVirus ReplicationAnimalsCell LineCricetinaeHost-Pathogen InteractionsImmunity, InnateSignal Transduction12C6+ heavy-ionBHK-21BHK-21 cell lineFMDVtranscription factor

Identifiers

PMID41574307
PMCPMC12819685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.