Evidence map›Paper›PMID 41574260›Full record

ArticleFrontiers in veterinary science2025

Temporal profiling of haptoglobin and cytokines in feedlot cattle with bovine respiratory disease.

Carol G Chitko-McKown, Bailey N Engle, Gary L Bennett, Larry A Kuehn, Keith D DeDonder, Michael D Apley, Gregory P Harhay, Michael L Clawson, Brad J White, Robert L Larson and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carol G Chitko-McKownUSDA-ARS US Meat Animal Research Center, Clay Center, NE, United States.
Bailey N EngleUSDA-ARS US Meat Animal Research Center, Clay Center, NE, United States.
Gary L BennettUSDA-ARS US Meat Animal Research Center, Clay Center, NE, United States.
Larry A KuehnUSDA-ARS US Meat Animal Research Center, Clay Center, NE, United States.
Keith D DeDonderCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Michael D ApleyCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Gregory P HarhayUSDA-ARS US Meat Animal Research Center, Clay Center, NE, United States.
Michael L ClawsonUSDA-ARS US Meat Animal Research Center, Clay Center, NE, United States.
Brad J WhiteCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Robert L LarsonCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Sarah F CapikCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Brian V LubbersCollege of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory cytokines and haptoglobin (HPT) were measured from 28 head of cattle that presented with bovine respiratory disease after being purchased and shipped to a common feedlot and assigned to either control or metaphylaxis treatment groups. Blood samples were obtained on the day of purchase (D0) and again at the time of diagnosis (S0) and 5 days after treatment (S5). Plasma was harvested and stored at -80 °C until assayed for the cytokines IFN-γ, IL-1β, IL-6, TNF-α, and HPT. Our objectives in this study were to determine differences between baseline (D0), day of diagnosis (S0) and post-treatment (S5), as well as to identify correlations among cytokine and HPT concentrations over time and by treatment. Interferon-gamma and IL-1β concentrations did not differ between D0 and S0 or S5. Tumor necrosis factor-

Indexed as

bovine respiratory diseasecattlecytokineshaptoglobininterferon-γinterleukin-1βinterleukin-6tumor necrosis factor-α

Identifiers

PMID41574260
PMCPMC12819287

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.