ArticleOrthopedic reviews2026
effect of poloxamer and hyaluronic acid administration in nerve root fibrosis and adhesion prevention following laminectomy: a novel bibliometric analysis.
Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Nerve root fibrosis (NRF) is a common postoperative complication following spinal decompression procedures and is associated with persistent pain and functional impairment. Although poloxamer and hyaluronic acid (HA) have been investigated as anti-adhesive agents, the global research landscape in this field has not been systematically evaluated. Methods: A bibliometric analysis was conducted using the Web of Science Core Collection to evaluate publications on poloxamer and HA for NRF prevention from 2000 to 2024. Citation analysis, co-authorship networks, and keyword co-occurrence including citation trends, co-authorship networks, and keyword co-occurrence mapping analysis were performed. Results: The final investigation comprised 42 relevant studies. The annually publishing trend indicated a considerable growth in research interest, with the largest number of publications in 2016(7 articles). Between 2020 and 2024, approximately 35% (15/42) of the total studies were published, indicating a growing focus on this field. The top contributing countries were Turkey (16 articles, 37.1%), China (13 articles, 30.2%), and Taiwan (7 articles, 16.3%). Citation analysis found that the most referenced journal was the Journal of Neurosurgery: Spine numbering 87 citations, followed by European Spine Journal (58 citations) and Neurosurgery Journal (55 citations). Co-citation analysis highlighted Mei-Hsiu C (70 citations) and Yu S (67 citations) as key researchers in this domain. Keyword mapping indicated that major research themes included "epidural fibrosis" (32 occurrences), "laminectomy" (24 occurrences), and "adhesion" (10 occurrences). Conclusion: Research on poloxamer and HA for NRF prevention has increased steadily, with emerging emphasis on inflammation modulation and biomaterial optimization. These findings provide a comprehensive overview of current trends and future research directions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.