Evidence map›Paper›PMID 41574135›Full record

ArticleNorthern clinics of Istanbul2025

Microwave ablation for hepatocellular carcinoma: A single-center experience and outcomes.

Mustafa Demir, Mehmet Taha Avci, Abdulbaki Agackiran, Sevdenur Emir, Aylin Acar, Tolga Canbak

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Article in Northern clinics of Istanbul, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mustafa DemirDepartment of Radiology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.
Mehmet Taha AvciDepartment of Radiology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.
Abdulbaki AgackiranDepartment of Radiology, Bahcesehir Unıversity Faculty of Medicine, Istanbul, Turkiye.
Sevdenur EmirDepartment of Radiology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.
Aylin AcarDepartment of General Surgery, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.
Tolga CanbakDepartment of General Surgery, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMicrowave ablation (MWA) has emerged as a minimally invasive treatment for hepatocellular carcinoma (HCC), offering a promising alternative for patients ineligible for surgical resection. This study aims to evaluate the efficacy, safety, and clinical outcomes of MWA in a single-center cohort, focusing on treatment success, recurrence rates, and long-term survival.

methodsA retrospective analysis was conducted on 54 patients who underwent percutaneous ultrasound-guided MWA for HCC between January 2019 and December 2023. Patient demographics, tumor characteristics, and procedural outcomes were assessed. Treatment success was defined as complete ablation confirmed by contrast-enhanced imaging one month post-procedure. Local tumor progression (LTP) and recurrence rates were evaluated during follow-up. Survival outcomes were analyzed based on follow-up data, considering overall survival and recurrence-free survival rate.

resultsA total of 71 tumors were treated in 54 patients. Complete ablation was achieved in 91.5% of tumors following the initial or secondary procedure. LTP was observed in 16.6% of patients during follow-up. No major complications were reported. The median follow-up period was 36 months, and survival outcomes were comparable to those reported for other ablative techniques. No statistically significant correlation was found between tumor size and ablation success (p>0.05).

conclusionMWA is an effective and safe treatment modality for HCC, demonstrating high technical success and acceptable recurrence rates. These findings support the continued integration of MWA in multidisciplinary HCC management, particularly for patients ineligible for surgery. Further research with larger cohorts and longer follow-up is needed to optimize patient selection and refine ablation strategies.

Indexed as

Hepatocellular carcinomaimage-guided ablationliver neoplasmsmicrowave ablationtumor recurrence

Identifiers

PMID41574135
PMCPMC12821121

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