Evidence map›Paper›PMID 41574053›Full record

ArticleClinical Medicine Insights. Oncology2026

Clinical Analysis of Peripheral Blood Indicators for Immune-Related Adverse Events (irAEs) in Patients With Advanced Lung Cancer.

Yin-Min Ji, Yu-Hui Qin, Ya-Hui Lv, Shu-Yan Xiao, Yi Dong, Zhi-Song Hu, Peng-Fei Cui, Tao Li, Xiao-Ran Cui, Yi Hu

Abstract read
In one paragraph

Article in Clinical Medicine Insights. Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yin-Min JiDepartment of Oncology, The Second Affiliated Hospital of Anhui Medical University, He Fei, China.
Yu-Hui QinDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University (State Key Laboratory of Digestive Health; National Clinical Research Center for Digestive Disease; Beijing Key Laboratory of Early Gastrointestinal Cancer Medicine and Medical Devices), Beijing, China.
Ya-Hui LvSenior Department of Oncology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Shu-Yan XiaoSenior Department of Oncology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yi DongSenior Department of Oncology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Zhi-Song HuMedical School of Chinese PLA, Beijing, China.
Peng-Fei CuiSenior Department of Oncology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Tao LiSenior Department of Oncology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-9038-4794
Xiao-Ran CuiSenior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Yi HuDepartment of Oncology, The Second Affiliated Hospital of Anhui Medical University, He Fei, China.ORCID https://orcid.org/0000-0001-9319-5692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Immune checkpoint inhibitors (ICIs) have revolutionized advanced lung cancer treatment, but immune-related adverse events (irAEs) remain a significant challenge. This study aimed to identify peripheral blood indicators associated with Immune-Related Adverse Events (irAEs) to improve early prediction and management. Methods: A retrospective analysis of 1910 advanced lung cancer cases treated with ICIs (2015-2024) was conducted. Patients were categorized into 2 groups: irAEs (n = 323) and control (n = 323). Peripheral blood indicators were analyzed at baseline and during treatment. Statistical analyses included t-tests, Mann-Whitney U tests, logistic regression, and Cox proportional hazards models. Results: Age (odds ratio [OR] = 0.96, Conclusion: Peripheral blood indicators are valuable for irAE prediction. Specifically, elevated NLR (hazard ratio [HR] = 1.14,

Indexed as

biomarkerscancer immunotherapyimmune checkpoint inhibitors (ICIs)immune-related adverse events (irAEs)Lung cancer

Identifiers

PMID41574053
PMCPMC12819973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.