Evidence map›Paper›PMID 41574022›Full record

ArticleBMJ open sport & exercise medicine2026

Effectiveness and acceptability of exercise treatments for adults with anxiety disorders: a systematic review and network meta-analysis.

Evander Fung-Chau Lei, Ke-Wen Wan, Zihan Dai, Bjorn T Tam

Abstract read
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Article in BMJ open sport & exercise medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Evander Fung-Chau LeiAcademy of Wellness and Human Development, Faculty of Arts and Social Sciences, Hong Kong Baptist University, Hong Kong, People's Republic of China.
Ke-Wen WanAcademy of Wellness and Human Development, Faculty of Arts and Social Sciences, Hong Kong Baptist University, Hong Kong, People's Republic of China.
Zihan DaiDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Bjorn T TamAcademy of Wellness and Human Development, Faculty of Arts and Social Sciences, Hong Kong Baptist University, Hong Kong, People's Republic of China.ORCID https://orcid.org/0000-0001-6740-8674

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anxiety disorders are persistent, functionally impairing conditions with high societal burden. In contrast, anxiety symptoms are elevated anxiety meeting scale thresholds (not formal diagnoses). While exercise is recognised as a complementary intervention for anxiety, the most effective mode of exercise for anxiety disorders remains unclear. Objective: To evaluate the effectiveness and acceptability of exercise treatments for adults with anxiety disorders via network meta-analysis. Methods: Systematic review and frequentist network meta-analysis were conducted, searching five databases (MEDLINE, EMBASE, PsycINFO, CENTRAL, SPORTDiscus) up to 1 March 2025. Treatments assessed included aerobic exercise, mind-body exercise (MBE), resistance training (RT), stretching, multicomponent exercise, cognitive-behavioral therapy, psychoeducation, waitlist control, usual care and placebo. Risk of bias was assessed using the Cochrane Risk of Bias Tool 2.0 (RoB 2.0). Outcomes included anxiety severity reduction (for effectiveness) and all-cause discontinuation rates (for acceptability). Results: 30 RCTs (1421 participants) were included: four had low risk, 19 some concerns and seven high risk. For combined anxiety conditions (anxiety disorders and symptoms), RT was most effective (standardised mean difference (SMD) -0.80, 95% CI -1.24 to -0.36, SUCRA 78.7%), followed by MBE (SMD -0.78, 95% CI -1.12 to -0.44, SUCRA 77.8%). For anxiety disorders, RT was most effective (SMD -0.79, 95% CI -1.18 to -0.40, SUCRA 78.5%) and MBE for anxiety symptoms (SMD -0.84, 95% CI -1.48 to -0.20, SUCRA 77.9%). No acceptability differences across treatments; network meta-regression showed diagnosis status did not alter effects. Conclusions: Both resistance exercise and MBE may be effective for anxiety disorders, with moderate certainty evidence. Acceptability remains unclear. Prospero registration number: CRD42024561238.

Indexed as

AnxietyEffectivenessExercises

Identifiers

PMID41574022
PMCPMC12820870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.