Evidence map›Paper›PMID 41573934›Full record

ArticlebioRxiv : the preprint server for biology2025

Tuberculous meningitis alters the proteomic landscape of brain-derived extracellular vesicles.

Blanca V Rodriguez, Nerketa N L Damiba, Nicole Beaubien, Daisy Puca, D Brian Foster, Samarjit Das, Elizabeth W Tucker

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Blanca V RodriguezDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
Nerketa N L DamibaDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
Nicole BeaubienDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
Daisy PucaDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
D Brian FosterDepartment of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
Samarjit DasDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
Elizabeth W TuckerDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287.

Funding

Pharmacology and Pharmacometrics CoreP30AI168436 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Petros C Karakousis · 2022 to 2026
$6.1M
Retinoid Metabolism in the Adult Heart and Heart FailureR01HL164478 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI D Brian Foster, MAUREEN A KANE · 2023 to 2026
$2.8M
Exosome-based Non-traditional Technologies Towards Multi-Parametric andIntegrated Approaches for SARS-CoV-2U18TR003780 · NCATS · JOHNS HOPKINS UNIVERSITY · PI DAS, SAMARJIT · 2021 to 2022
$2.0M
Novel Imaging and host-directed therapy in pediatric CNS TBK08AI139371 · NIAID · JOHNS HOPKINS UNIVERSITY · PI TUCKER, ELIZABETH WINANS · 2019 to 2023
$994k
NCATS NIH HHS U18 TR003780NHLBI NIH HHS R01 HL164478NIAID NIH HHS K08 AI139371NIAID NIH HHS P30 AI168436
6 · The paper itself

Abstract

Tuberculous meningitis (TB meningitis), the deadliest form of

Indexed as

extracellular vesiclesmicroglial activationneuroinflammationproteomicsTuberculous meningitis

Identifiers

PMID41573934
PMCPMC12822729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.