Evidence map›Paper›PMID 41573927›Full record

ArticlebioRxiv : the preprint server for biology2025

Protein kinase F regulates the virulence of

Flor Torres-Juarez, Shivangi Rastogi, David Young, Paul J Baker, Viplov K Biswas, Shannon E Khan, D Branch Moody, Katrin D Mayer-Barber, Volker Briken

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Flor Torres-JuarezInflammation and Innate Immunity Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
Shivangi RastogiDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA.ORCID 0000-0002-0046-0045
David YoungDivision of Rheumatology, Immunity and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Paul J BakerInflammation and Innate Immunity Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
Viplov K BiswasDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA.
Shannon E KhanDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA.
D Branch MoodyDivision of Rheumatology, Immunity and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Katrin D Mayer-BarberInflammation and Innate Immunity Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
Volker BrikenDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA.ORCID 0000-0001-5830-6107

Funding

Study of M. tuberculosis under human host selection to identify virulence and barrier lipids (Project 1)U19AI162584 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2021 to 2025
$13.5M
Chemical Biological Discovery of Lipid Virulence Factors in the Major Bacterial PathogensR01AI165573 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2022 to 2025
$3.0M
Manipulation of the host cell inflammasome by Mycobacterium tuberculosisR01AI147630 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI VOLKER BRIKEN · 2021 to 2026
$3.0M
NIAID NIH HHS R01 AI147630NIAID NIH HHS R01 AI165573NIAID NIH HHS U19 AI162584
6 · The paper itself

Abstract

The serine/threonine protein kinase F (PknF) of

Identifiers

PMID41573927
PMCPMC12822562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.