Evidence map›Paper›PMID 41573673›Full record

ReviewInnovation in aging2026

Associations of social isolation and loneliness with healthcare utilization among older adults: a systematic review and meta-analysis.

Tianxue Hou, Mu-Hsing Ho, Zohar Lederman, Denise Shuk Ting Cheung, Timothy Hudson Rainer, Chia-Chin Lin

Abstract readReview
In one paragraph

Review in Innovation in aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tianxue HouSchool of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Mu-Hsing HoSchool of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-9443-4082
Zohar LedermanDepartment of Emergency Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Denise Shuk Ting CheungSchool of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-8741-9271
Timothy Hudson RainerDepartment of Emergency Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Chia-Chin LinSchool of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0001-5101-0266

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Social isolation and loneliness are significant public health concerns associated with increased healthcare utilization among older adults. This review aims to synthesize evidence on the associations between social isolation, loneliness, and healthcare utilization. Research Design and Methods: Five databases were searched from inception to March 21, 2025, using keyword groups related to social isolation/loneliness, older adults, and healthcare utilization (primary care, emergency visits, inpatient care, and outpatient care). Methodological quality was assessed using the Newcastle-Ottawa Scale. Random-effects models were employed to pool effect sizes (incidence rate ratios [IRRs], odds ratios [ORs]). Results: A total of 44 studies were included in the systematic review, and 34 were included in the meta-analysis ( Discussion and Implications: This is the first meta-analysis to comprehensively synthesize the associations between social isolation, loneliness, and 4 types of healthcare utilization among older adults. The findings highlight the importance of addressing social isolation and loneliness as potential strategies to reduce avoidable healthcare utilization.

Indexed as

Emergency department visitInpatient careOutpatient carePrimary care

Identifiers

PMID41573673
PMCPMC12822840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.