TACE combined with sorafenib induces complete remission in an elderly patient with hepatocellular carcinoma, hepatic venous tumor thrombus, and diffuse lung metastasis: a case study and literature review.

Zhao Guangsheng, Liu Song, Yin Shunhang, Ding Zhongyi, Tang Shunxiong, Zhou Jun, Zhang Yuewei

Abstract readCase Reports

In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhao Guangsheng *Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.

Liu Song *Dalian Medical University, Dalian, Liaoning, China.

Yin ShunhangCancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.

Ding ZhongyiCancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.

Tang ShunxiongCancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.

Zhou JunCancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.

Zhang YueweiHepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) with hepatic venous tumor thrombus (HVTT) and synchronous lung metastases has a poor prognosis and limited treatment options. We present a 70-year-old male with chronic hepatitis B and BCLC stage C HCC, featuring a large liver tumor (14×12×10 cm), HVTT, and diffuse lung metastases. The patient was treated with transarterial gene embolization (TAGE) using gelatin sponge microparticles and rAd-p53 (Gendicine

Indexed as

gelatin sponge particleshepatocellular carcinomarecombinant adenovirus p53 injectionsorafenibtranscatheter arterial chemoembolization

Identifiers

PMID41573652

DOI10.3389/fonc.2025.1693092

PMCPMC12819251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.