Evidence map›Paper›PMID 41573482›Full record

ArticleCureus2025

Stepwise Management of Refractory Ventricular Arrhythmias in Desmoplakin Cardiomyopathy: A Case Report.

Grace Ibitamuno, Erica D Wittwer, Ruben J Crespo-Diaz, Mauricio A Villavicencio, Brendan T Wanta

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Grace IbitamunoAnesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, USA.
Erica D WittwerAnesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, USA.
Ruben J Crespo-DiazCardiovascular Medicine, Mayo Clinic, Rochester, USA.
Mauricio A VillavicencioCardiovascular Surgery, Mayo Clinic, Rochester, USA.
Brendan T WantaAnesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Desmoplakin cardiomyopathy is a rare, genetic condition that often leads to dangerous arrhythmias, ventricular scarring, and eventual heart failure. Here, the case of a 50-year-old woman suffering from both ventricular storm and biventricular heart failure is discussed. Her ventricular tachycardia proved resistant to several antiarrhythmic medications, which made it difficult to maintain proper cardiac output. To stabilize her condition temporarily, a stellate ganglion block was performed until she could undergo successful orthotopic heart transplantation. When antiarrhythmic drugs are unsuitable or fail to control electrical storms, stellate ganglion blockade presents a valid alternative. For patients with desmoplakin cardiomyopathy, especially when combined with mechanical circulatory support, this approach can serve as an effective bridge to cardiac transplant.

Indexed as

arrhythmogenicitycardiac transplantationcardiomyopathydesmoplakinmechanical circulatory supportstellate ganglion block

Identifiers

PMID41573482
PMCPMC12819077

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.