Evidence map›Paper›PMID 41573473›Full record

ReviewCureus2025

The Impact of Childhood Maltreatment on the Development of Borderline Personality Disorder in Adolescents: A Narrative Review.

Mustafa A Alhammad, Hayat M Alshammari, Nouf W Alnafea, Kady S Althunayyan, Walaa S Mohammed, Manar M Almohamadi

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mustafa A AlhammadInternal Medicine, King Abdulaziz University, Jeddah, SAU.
Hayat M AlshammariPsychiatry, Irada Mental Health Hospital, Qassim, SAU.
Nouf W AlnafeaPsychiatry, King Saud University Medical City, Riyadh, SAU.
Kady S AlthunayyanMedicine, Qassim University, Buraydah, SAU.
Walaa S MohammedPsychiatry, Al-Dammam Medical Complex, Al-Dammam, SAU.
Manar M AlmohamadiPsychiatry, King Abdulaziz University, Jeddah, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of early life trauma on the emergence of borderline personality symptoms has been extensively researched. However, despite the established correlation between childhood maltreatment and borderline personality disorder (BPD), the specific types of trauma and the mediating pathways remain insufficiently mapped. While sexual abuse has received substantial attention due to its measurable clinical impact, the roles of withdrawal and emotional neglect lack early detection and intervention during childhood. Understanding the multifactorial origins of BPD is essential for developing early preventive strategies and effective therapeutic models. This review discusses how the multiple and cumulative effects of maltreatment, including omission-type maltreatment such as emotional neglect, may contribute to the development of BPD through both physical and psychological mediators. This narrative review emphasizes the necessity of recognizing invisible or under-addressed trauma types, proposing conceptual pathways, and informing trauma-informed care focused on the physical, emotional, and social safety of children and adolescents.

Indexed as

adolescentsadverse childhood experienceborderline personality disorderchildhood maltreatmentemotional dysregulationetiopathogenesismediatorneglect

Identifiers

PMID41573473
PMCPMC12820898

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.