Evidence map›Paper›PMID 41573424›Full record

ArticleCureus2025

Hepatic Teratoma: An Unusual Presentation of a Germ Cell Neoplasm.

Muthu M Manickam, Ashwin Kumar, G Murugan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Muthu M ManickamRadiodiagnosis, Sree Balaji Medical College and Hospital, Chennai, IND.
Ashwin KumarRadiodiagnosis, Barnard Institute of Radiology, Madras Medical College, Chennai, IND.
G MuruganRadiology, Sree Balaji Medical College and Hospital, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hepatic teratoma is an exceptionally rare germ cell tumor. Its pathogenesis in the liver, an uncommon site for germ cell tumors, remains poorly understood. We present a case of a primary hepatic teratoma in a young adult female to highlight its clinical presentation, radiological hallmarks, and management. A 20-year-old female presented with a five-month history of dull, aching pain in the upper abdomen. Physical examination revealed a non-tender, palpable mass in the right hypochondrium. Routine blood investigations, including liver function tests and serum alpha-fetoprotein, were within normal limits. Contrast-enhanced computed tomography of the abdomen revealed a large, well-defined heterodense mass (~10.2 x 5.3 cm) in the liver. The mass exhibited characteristic heterogeneity with components of fat, calcification, and soft tissue, creating a mass effect on adjacent abdominal vessels. Based on the imaging findings, a provisional diagnosis of a complex benign tumor, likely a teratoma, was made. The patient underwent a successful surgical resection. Histopathological examination confirmed the presence of mature tissues derived from all three germ layers, leading to the definitive diagnosis of a mature cystic teratoma of the liver. This case underscores that primary hepatic teratoma, while exceedingly rare, should be considered in the differential diagnosis of a complex, heterogeneous liver mass, particularly in young patients. Cross-sectional imaging is pivotal in suggesting the diagnosis by identifying pathognomonic elements like fat and calcification. Complete surgical excision remains the cornerstone of treatment and is typically curative for mature lesions, emphasizing the importance of accurate radiological and histopathological correlation.

Indexed as

case reportct abdomengerm cell tumorliver neoplasmprimary hepatic teratoma

Identifiers

PMID41573424
PMCPMC12819354

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.