Evidence map›Paper›PMID 41573401›Full record

ArticleFrontiers in neurology2025

Drug-coated balloon versus conventional balloon for stent angioplasty in symptomatic intracranial atherosclerotic stenosis.

Lili Sun, Chao Chen, Wei Zhao, Yun Song, Meimei Zheng, Hao Yin, Jun Zhang, Yao Meng, Wei Wang, Weili Li and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lili SunDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Chao ChenDepartment of Gerontology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Wei ZhaoDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Yun SongDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Meimei ZhengDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Hao YinDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Jun ZhangDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Yao MengDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Wei WangDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Weili LiDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Chenlu ZhuDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.
Ju HanDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Due to limited evidence on the optimal strategy for intracranial atherosclerotic stenosis (ICAS), further evidence on the safety and efficacy of drug-coated balloon (DCB) predilation stent angioplasty was aimed to be provided. Methods: Consecutive patients with symptomatic medically refractory ICAS from January 2016 to November 2022 who underwent balloon predilation stent angioplasty were retrospectively analyzed and dichotomized by whether DCB or conventional balloon (CB) was used. The efficacy and safety endpoints were compared by propensity score matching. Results: A total of 95 patients in the DCB group and 100 patients in the CB group were selected. Of these, 134 patients were matched. The in-stent restenosis (ISR) incidence (1.5% vs. 16.4%, Conclusion: Compared with CB predilation stent angioplasty, DCB predilation stent angioplasty effectively reduced the degree of restenosis and the risk of ISR, but had no advantage in terms of symptomatic restenosis risk currently. However, these findings should be interpreted cautiously because of the aforementioned limitations, and prospective multicenter randomized studies with larger patient number will be required to establish the efficacy and safety of DCB.

Indexed as

drug-coated balloonin-stent restenosisintracranial atherosclerotic stenosisstent angioplastystroke

Identifiers

PMID41573401
PMCPMC12819204

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.