Evidence map›Paper›PMID 41573391›Full record

ArticleFrontiers in neurology2025

Structural brain MRI abnormalities in

Daewoong Ahn, Daehyun Kim, Hyeon Deok Sang, Heeseung Cho, Ara Ko, Na-Young Shin, Hoon-Chul Kang, Joon Soo Lee, Lip-Yuen Teng, Se Hee Kim

Abstract read
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In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daewoong Ahn *Yonsei University College of Medicine, Seoul, Republic of Korea.
Daehyun Kim *Yonsei University College of Medicine, Seoul, Republic of Korea.
Hyeon Deok SangDivision of Pediatric Neurology, Severance Children's Hospital, Seoul, Republic of Korea.
Heeseung ChoDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea.
Ara KoDivision of Pediatric Neurology, Severance Children's Hospital, Seoul, Republic of Korea.
Na-Young ShinDepartment of Radiology, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.
Hoon-Chul KangDivision of Pediatric Neurology, Severance Children's Hospital, Seoul, Republic of Korea.
Joon Soo LeeDivision of Pediatric Neurology, Severance Children's Hospital, Seoul, Republic of Korea.
Lip-Yuen TengPediatric Neurology Unit, Department of Pediatrics, Hospital Tuanku Ja'afar, Seremban, Malaysia.
Se Hee KimDivision of Pediatric Neurology, Severance Children's Hospital, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To characterize the prevalence and patterns of structural brain magnetic resonance imaging (MRI) abnormalities in children with genetically confirmed Methods: We retrospectively analyzed brain MRI findings from a single-center cohort of 139 pediatric patients with pathogenic variants of Results: MRI abnormalities were identified in 52 of the 139 patients (37.4%). The most common findings were atrophy (21.6%), hippocampal abnormalities (6.5%), white matter signal abnormalities (5.0%) and hypoxic-ischemic encephalopathy (3.6%). Abnormalities were most frequent in the Conclusion: Contrary to earlier assumptions, structural MRI abnormalities are common in

Indexed as

Dravet syndromeepilepsyepileptic encephalopathiesgeneticneurodevelopmental disorderssodium channelopathiessodium channels

Identifiers

PMID41573391
PMCPMC12819171

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.