ArticleTransplant international : official journal of the European Society for Organ Transplantation2025
Age-Related Risk After Kidney Transplantation: A Comprehensive Analysis of Infection Burden, Graft Outcomes, and Mortality.
Article in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prediction models for infection after kidney transplantation: a systematic review.Frontiers in medicine · 2026Pooled it
- Peritoneal Dialysis-Related Peritonitis and Kidney Transplant Outcomes.JAMA network open · 2026Article
- Renal transplantation in older recipients - results of the DZIF transplant cohort.BMC geriatrics · 2026Article
- Association of remnant cholesterol with long-term outcomes in kidney transplant recipients: a retrospective cohort study.Lipids in health and disease · 2026Article
- Pathogen-specific epidemiology and clinical trajectories of fungal infections after kidney transplantation: a prospective multicenter cohort study.BMC infectious diseases · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Given the increasing number of kidney transplantation in elderly recipients, understanding age-specific risks is essential for optimized post-transplant care. We analyzed 572 kidney transplant recipients from the DZIF Transplant Cohort (2012-2023), stratified by age: <40 (n = 146), 40-60 (n = 279), >60 years (n = 147). Outcomes included infection burden, graft outcomes, and mortality over a median follow-up of 5 years. Multivariable Cox models with inverse probability weighting, adjusted for clinical confounders, was applied. In older recipients, the unadjusted 5-year rates of graft failure, mortality, and infections were significantly higher-both overall and for specific types, including pneumonia, urinary tract infections, invasive opportunistic infections, and multidrug-resistant infections. After adjustment, age remained only independently associated with mortality (HR = 6.21, p = 0.02), but not with overall infection burden or graft loss. Older patients exhibited a shift in pathogen prevalence, particularly for
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