Impact of Body Mass Index on Clinical Outcomes After Thrombectomy for Acute Ischemic Stroke in a Japanese Population.

Background: We aimed to determine the impact of body mass index (BMI) on outcomes in Japanese patients undergoing mechanical thrombectomy for acute ischemic stroke using a Japanese obesity cutoff. Methods: The study sample consisted of consecutive patients undergoing thrombectomy for acute ischemic stroke at our institution from January 2020 to December 2023. Patients were divided into 3 groups by BMI: low (<18.5 kg/m Results: A total of 309 patients were analyzed, of whom 39 (12.6%) had a low BMI, 201 (65.0%) had a normal BMI, and 69 (22.3%) had a high BMI. There were significant differences in the nutritional status index scores between the 3 groups, namely the Geriatric Nutritional Risk Index, the Controlling Nutritional Status, and the Prognostic Nutritional Index. However, there were no significant differences in procedural and safety outcomes. There was no significant difference in the proportion of patients with a modified Rankin Scale score of 0-2 at 90 days between the 3 groups. However, there were significant differences in the proportion of patients with a modified Rankin Scale score of 0-3 (overall 51.8%; low 35.9%, normal 51.7%, high 60.9%; Conclusions: In a Japanese population, low BMI may be associated with poor clinical outcomes after thrombectomy for acute ischemic stroke, including increased mortality.