Evidence map›Paper›PMID 41573254›Full record

ReviewFrontiers in surgery2025

Risk factors for recurrent laryngeal nerve injury following thyroid surgery: a systematic review and meta-analysis.

Xiang Yang, Wuzhou Ouyang, Peng Ma

Abstract readReview
In one paragraph

Review in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiang YangBeijing Anzhen Nanchong Hospital of Capital Medical University & Nanchong Central Hospital, Nanchong, China.
Wuzhou OuyangSichuan Nanchong No. 1 Middle School, Nanchong, China.
Peng MaBeijing Anzhen Nanchong Hospital of Capital Medical University & Nanchong Central Hospital, Nanchong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recurrent laryngeal nerve injury is one of the most common and severe complications in thyroid surgery, potentially leading to postoperative hoarseness, dysphagia, or even airway obstruction. Although numerous studies have investigated its risk factors, findings remain inconsistent. This systematic review and meta-analysis aim to synthesize existing evidence and explore risk factors for recurrent laryngeal nerve injury following thyroid surgery. Methods: A systematic search was conducted in PubMed, Embase, Web of Science, and the Cochrane Library databases from their inception to October 1, 2025, to identify observational studies and randomized controlled trials investigating risk factors for recurrent laryngeal nerve injury following thyroid surgery. Two researchers independently performed literature screening, data extraction, and quality assessment using the Newcastle-Ottawa Scale (NOS). Stata 15 software was used to calculate pooled odds ratios (OR) and 95% confidence intervals (CI). Results: A total of 20 articles( Conclusion: This study indicates that older age, female gender, extended thyroidectomy, lymph node dissection, reoperation, retrosternal goiter, and absence of nerve monitoring mya be independent risk factors for recurrent laryngeal nerve injury following thyroid surgery. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251106124, identifier CRD420251106124.

Indexed as

meta-analysisrecurrent laryngeal nerve injuryrisk factorssystematic reviewthyroid surgery

Identifiers

PMID41573254
PMCPMC12819817

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.